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Richard Scott Klasco

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Emergency Medicine

    Collapse Biography 
    Collapse education and training
    Harvard Medical SchoolMD06/1990Medicine
    Brigham and Women’s HospitalResident06/1992Internal Medicine
    Denver Health Emergency MedicineChief Resident04/1995Emergency Medicine

    Collapse Overview 
    Collapse overview
    The thrust of my career has been to render evidence operational. This means making the right thing to do, the easy thing to do. I have pursued this goal in academia, industry, policy, and in the press.

    In academia, I have published original articles in peer-reviewed journals, such as JAMA; have lectured at leading academic medical centers (e.g., Harvard, Stanford, Mayo, UCSF); and sat on national and state-level committees (e.g., Healthcare Information and Management Systems Society [HIMSS], Colorado Poison Control Oversight Board). As an Instructor at Harvard Medical School I served on the Executive Committee of Brigham and Women’s Hospital Center for Patient Safety Research and Practice and was an Attending Physician in the Department of Emergency Medicine at the Beth Israel Deaconess Medical Center, where I cared for patients in a Level I trauma center, taught residents and medical students, and served on the department’s quality assurance committee.

    In industry, I served as the senior clinician for several clinical decision support companies in the U.S. In this capacity, I was the Chief Medical Officer and Editor-in-Chief for the Thomson Reuters group of healthcare companies and had editorial responsibility for a portfolio of information companies that included Micromedex, the Physicians’ Desk Reference (PDR), and the United States Pharmacopoeia (USP) Drug Information. For the last eight years, I have been the CMO for Motive Medical Intelligence, a San Francisco-based clinical decision support company

    In policy, I have been an advocate for governmental adoption of evidence-based clinical decision support. At the state level, I served as a Colorado member of the Pew Prescription Project supporting the passage of the Physician Payments Sunshine Act and received a gubernatorial appointment overseeing poison control centers. Nationally, I testified before the United States Congress on evidence-based practices and won CMS approval for an officially designated compendium of evidence-based oncologic drug information. The purpose of this work was to provide a regulatory mandate for payers to use evidence-based information in their reimbursement decisions and to restrict undue influence on the part of pharmaceutical companies on physicians prescribing practices.

    In the press, I have written many original articles for publications such as the New York Times and the Washington Post. The theme of these articles has been to communicate complex medical topics effectively to a lay audience.

    My goal is to speed the translation of research into practice by incorporating advanced decision support into electronic systems — such as electronic medical records and computerized physician order entry — using technology (e.g., metadata tagging, rules engines, controlled vocabularies, and taxonomies) to transform flat text into patient-specific guidance that can be delivered in real-time within the physician’s workflow.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Klasco, Richard. New York Times. How Many People Can’t Tolerate Statins?. 2018.
    2. Klasco, Richard. New York Times. Can Lifestyle Changes Remove Plaques in Your Arteries?. 2018.
    3. Klasco, Richard; Glinert, Lewis. Washington Post. ‘What did the doctor say?’: A simple question with a difficult answer. 2018.
    4. Klasco RS, Glinert LH. Legal Ramifications of Ambiguous Clinical Guidelines-Reply. JAMA. 2017 05 16; 317(19):2020-2021. PMID: 28510676.
      View in: PubMed
    5. Klasco RS, Glinert LH. Language for Actionable Recommendations in Clinical Guidelines: Avoiding Hedging and Equivocation. JAMA. 2017 02 14; 317(6):583-584. PMID: 28196262.
      View in: PubMed
    6. Klasco RS, Wolfe RE, Lee T, Anderson P, Jacobson LS, Solano J, Edlow J, Grossman SA. Can medical record reviewers reliably identify errors and adverse events in the ED? Am J Emerg Med. 2016 Jun; 34(6):1043-8. PMID: 27055604.
      View in: PubMed
    7. Klasco RS, Wolfe RE, Wong M, Edlow J, Chiu D, Anderson PD, Grossman SA. Assessing the rates of error and adverse events in the ED. Am J Emerg Med. 2015 Dec; 33(12):1786-9. PMID: 26458533.
      View in: PubMed
    8. Chase M, Klasco RS, Joyce NR, Donnino MW, Wolfe RE, Shapiro NI. Predictors of bacteremia in emergency department patients with suspected infection. Am J Emerg Med. 2012 Nov; 30(9):1691-7. PMID: 22626814.
      View in: PubMed
    9. Klasco, Richard. Drugdex® system. MICROMEDEX® Healthcare Series. Thomson Healthcare. 2003.
    10. Klasco R. Colorado tick fever. Med Clin North Am. 2002 Mar; 86(2):435-40, ix. PMID: 11982311.
      View in: PubMed
    11. Handler JA, Gillam M, Sanders AB, Klasco R. Defining, identifying, and measuring error in emergency medicine. Acad Emerg Med. 2000 Nov; 7(11):1183-8. PMID: 11073465.
      View in: PubMed
    12. Hartoch RS, Klasco RS. Clinicopathological conference: young man with syncope. Acad Emerg Med. 1995 Oct; 2(10):934-8. PMID: 8542497.
      View in: PubMed
    13. Klasco, Richard. USP DI® Drug Information for the Health Care Professional.
    14. Klasco, Richard. POISINDEX® System. Thomson Reuters.
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