High-risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells.
Young FM, Campbell A, Emo KL, Jansson J, Wang PY, Jordan CT, Mullen CA. High-risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells. Biol Blood Marrow Transplant. 2008 Jun; 14(6):622-30.
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Animals
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Apoptosis
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Bone Marrow Transplantation
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Cells, Cultured
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Cyclin-Dependent Kinase Inhibitor p16
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Disease Progression
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Fusion Proteins, bcr-abl
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Genes, abl
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Genes, p16
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Graft vs Leukemia Effect
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Humans
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Killer Cells, Natural
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Male
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Mice
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Mice, Inbred C57BL
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Mice, Knockout
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Minor Histocompatibility Antigens
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Models, Immunological
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Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
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Radiation Chimera
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T-Lymphocyte Subsets
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T-Lymphocytes, Cytotoxic
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Transplantation, Homologous