T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes.
Pauza ME, Dobbs CM, He J, Patterson T, Wagner S, Anobile BS, Bradley BJ, Lo D, Haskins K. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes. 2004 Apr; 53(4):978-88.
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Animals
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Autoantigens
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CD4-Positive T-Lymphocytes
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CD8-Positive T-Lymphocytes
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Chromosome Mapping
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Diabetes Mellitus
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Disease Susceptibility
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DNA Primers
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Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
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Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
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Humans
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Mice
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Mice, Inbred BALB C
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Mice, Inbred NOD
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Mice, Transgenic
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Polymorphism, Genetic
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Promoter Regions, Genetic
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Receptors, Antigen, T-Cell
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Reverse Transcriptase Polymerase Chain Reaction
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RNA, Small Interfering
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T-Lymphocytes