Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Title: Long-Term Oxygen Treatment Trial (LOTT) - Data Coordinating Center

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The Long-term Oxygen Treatment Trial (LOTT) is a randomized controlled clinical trial to assess the efficacy of around-the-clock, supplemental oxygen therapy in subjects with chronic obstructive pulmonary disease (COPD) and moderately severe hypoxemia. Mortality and quality of life are the major outcome measures. LOTT involves a Data Coordinating Center and 14 Regional Clinical Centers.
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