Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Prafulla Aryal

TitleResearch Associate
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM - Physiology
Phone303/724-4909

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Trick JL, Chelvaniththilan S, Klesse G, Aryal P, Wallace EJ, Tucker SJ, Sansom MS. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure. 2016 Dec 06; 24(12):2207-2216. PMID: 27866853.
      View in: PubMed
    2. McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states. J Gen Physiol. 2016 Jun; 147(6):497-505. PMID: 27241700.
      View in: PubMed
    3. Trick JL, Aryal P, Tucker SJ, Sansom MS. Molecular simulation studies of hydrophobic gating in nanopores and ion channels. Biochem Soc Trans. 2015 Apr; 43(2):146-50. PMID: 25849908.
      View in: PubMed
    4. Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, Sansom MS, Tucker SJ, Carpenter EP. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science. 2015 Mar 13; 347(6227):1256-9. PMID: 25766236.
      View in: PubMed
    5. Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel. Channels (Austin). 2015; 9(1):44-9. PMID: 25487004.
      View in: PubMed
    6. Aryal P, Sansom MS, Tucker SJ. Hydrophobic gating in ion channels. J Mol Biol. 2015 Jan 16; 427(1):121-30. PMID: 25106689.
      View in: PubMed
    7. Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel. Nat Commun. 2014 Jul 08; 5:4377. PMID: 25001086.
      View in: PubMed
    8. Almeida MC, Hew-Butler T, Soriano RN, Rao S, Wang W, Wang J, Tamayo N, Oliveira DL, Nucci TB, Aryal P, Garami A, Bautista D, Gavva NR, Romanovsky AA. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. J Neurosci. 2012 Feb 08; 32(6):2086-99. PMID: 22323721.
      View in: PubMed
    9. An MC, Lin W, Yang J, Dominguez B, Padgett D, Sugiura Y, Aryal P, Gould TW, Oppenheim RW, Hester ME, Kaspar BK, Ko CP, Lee KF. Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10702-7. PMID: 20498043.
      View in: PubMed
    10. Aryal P, Dvir H, Choe S, Slesinger PA. A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci. 2009 Aug; 12(8):988-95. PMID: 19561601.
      View in: PubMed
    11. Fowler CE, Aryal P, Suen KF, Slesinger PA. Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. J Physiol. 2007 Apr 01; 580(Pt 1):51-65. PMID: 17185339.
      View in: PubMed
    12. Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19; 46(4):569-79. PMID: 15944126.
      View in: PubMed
    13. Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. J Biol Chem. 2005 Jan 07; 280(1):669-76. PMID: 15492008.
      View in: PubMed
    14. Dance AL, Miller M, Seragaki S, Aryal P, White B, Aschenbrenner L, Hasson T. Regulation of myosin-VI targeting to endocytic compartments. Traffic. 2004 Oct; 5(10):798-813. PMID: 15355515.
      View in: PubMed
    15. Lucas DT, Aryal P, Szweda LI, Koch WJ, Leinwand LA. Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2003 Feb; 284(2):H575-83. PMID: 12414446.
      View in: PubMed
    Aryal's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)