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William Kent Cornwell

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Overview 
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    Translational research on cerebrovascular and cardiovascular reflexes at rest and during exercise among elite athletes, patients with heart failure and those requiring mechanical circulatory support. Emphasis on cardiovascular hemodynamics and generation of ventricular pressure-volume loops in real time, exercise pressor reflexes, barereceptor physiology and adrenergic signaling. I will be serving as a cardiology mentor for the 2018-2019 academic year.


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Purohit SN, Cornwell WK, Pal JD, Lindenfeld J, Ambardekar AV. Living Without a Pulse: The Vascular Implications of Continuous-Flow Left Ventricular Assist Devices. Circ Heart Fail. 2018 Jun; 11(6):e004670. PMID: 29903893.
      View in: PubMed
    2. Werner GDA, Cornelissen JHC, Cornwell WK, Soudzilovskaia NA, Kattge J, West SA, Kiers ET. Symbiont switching and alternative resource acquisition strategies drive mutualism breakdown. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):5229-5234. PMID: 29712857.
      View in: PubMed
    3. Zanne AE, Pearse WD, Cornwell WK, McGlinn DJ, Wright IJ, Uyeda JC. Functional biogeography of angiosperms: life at the extremes. New Phytol. 2018 Jun; 218(4):1697-1709. PMID: 29603243.
      View in: PubMed
    4. Howden EJ, Sarma S, Lawley JS, Opondo M, Cornwell W, Stoller D, Urey MA, Adams-Huet B, Levine BD. Reversing the Cardiac Effects of Sedentary Aging in Middle Age-A Randomized Controlled Trial: Implications For Heart Failure Prevention. Circulation. 2018 Apr 10; 137(15):1549-1560. PMID: 29311053.
      View in: PubMed
    5. Luc JGY, Pierre CA, Phan K, Vahedein YS, Liberson AS, Cornwell WK, Phillips SJ, Tchantchaleishvili V. Fluid structure interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular assist devices. Int J Artif Organs. 2017 Nov 16; 0. PMID: 29148023.
      View in: PubMed
    6. Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK, Poh PYS, Stoller D, Levine BD, Crandall CG. Volume loading augments cutaneous vasodilatation and cardiac output of heat stressed older adults. J Physiol. 2017 Oct 15; 595(20):6489-6498. PMID: 28833129.
      View in: PubMed
    7. Cornelissen JHC, Grootemaat S, Verheijen LM, Cornwell WK, van Bodegom PM, van der Wal R, Aerts R. Are litter decomposition and fire linked through plant species traits? New Phytol. 2017 Nov; 216(3):653-669. PMID: 28892160.
      View in: PubMed
    8. Wang H, Prentice IC, Keenan TF, Davis TW, Wright IJ, Cornwell WK, Evans BJ, Peng C. Towards a universal model for carbon dioxide uptake by plants. Nat Plants. 2017 Sep; 3(9):734-741. PMID: 29150690.
      View in: PubMed
    9. Cornwell W, Nakagawa S. Phylogenetic comparative methods. Curr Biol. 2017 May 08; 27(9):R333-R336. PMID: 28486113.
      View in: PubMed
    10. Pandey A, Cornwell WK, Willis B, Neeland IJ, Gao A, Leonard D, DeFina L, Berry JD. Body Mass Index and Cardiorespiratory Fitness in Mid-Life and Risk of Heart Failure Hospitalization in Older Age: Findings From the Cooper Center Longitudinal Study. JACC Heart Fail. 2017 May; 5(5):367-374. PMID: 28396043.
      View in: PubMed
    11. Patel AC, Dodson RB, Cornwell WK, Hunter KS, Cleveland JC, Brieke A, Lindenfeld J, Ambardekar AV. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices. JACC Heart Fail. 2017 Jun; 5(6):449-459. PMID: 28285118.
      View in: PubMed
    12. Bastias CC, Fortunel C, Valladares F, Baraloto C, Benavides R, Cornwell W, Markesteijn L, de Oliveira AA, Sansevero JB, Vaz MC, Kraft NJ. Intraspecific leaf trait variability along a boreal-to-tropical community diversity gradient. PLoS One. 2017; 12(2):e0172495. PMID: 28241033.
      View in: PubMed
    13. Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Mar 15; 595(6):2115-2127. PMID: 28092926.
      View in: PubMed
    14. Zhao W, Cornwell WK, van Pomeren M, van Logtestijn RS, Cornelissen JH. Species mixture effects on flammability across plant phylogeny: the importance of litter particle size and the special role for non-Pinus Pinaceae. Ecol Evol. 2016 11; 6(22):8223-8234. PMID: 27878090.
      View in: PubMed
    15. Maherali H, Oberle B, Stevens PF, Cornwell WK, McGlinn DJ. Mutualism Persistence and Abandonment during the Evolution of the Mycorrhizal Symbiosis. Am Nat. 2016 Nov; 188(5):E113-E125. PMID: 27788343.
      View in: PubMed
    16. Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK, Poh PY, Stoller D, Levine BD, Crandall CG. Healthy aging does not compromise the augmentation of cardiac function during heat stress. J Appl Physiol (1985). 2016 Oct 01; 121(4):885-892. PMID: 27609201.
      View in: PubMed
    17. Ye D, Liu G, Song YB, Cornwell WK, Dong M, Cornelissen JH. Strong but diverging clonality - climate relationships of different plant clades explain weak overall pattern across China. Sci Rep. 2016 06 01; 6:26850. PMID: 27246203.
      View in: PubMed
    18. Darsaklis K, Dickson ME, Cornwell W, Ayers CR, Torres F, Chin KM, Matulevicius S. Right atrial emptying fraction non-invasively predicts mortality in pulmonary hypertension. Int J Cardiovasc Imaging. 2016 Jul; 32(7):1121-30. PMID: 27076226.
      View in: PubMed
    19. Cornwell WK, Tarumi T, Stickford A, Lawley J, Roberts M, Parker R, Fitzsimmons C, Kibe J, Ayers C, Markham D, Drazner MH, Fu Q, Levine BD. Restoration of Pulsatile Flow Reduces Sympathetic Nerve Activity Among Individuals With Continuous-Flow Left Ventricular Assist Devices. Circulation. 2015 Dec 15; 132(24):2316-22. PMID: 26510698.
      View in: PubMed
    20. Temme AA, Liu JC, Cornwell WK, Cornelissen JH, Aerts R. Winners always win: growth of a wide range of plant species from low to future high CO2. Ecol Evol. 2015 Nov; 5(21):4949-61. PMID: 26640673; PMCID: PMC4662314.
      View in: PubMed, PubMed Central
    21. Cornwell WK, Urey M, Drazner MH, Levine BD. Continuous-Flow Circulatory Support: The Achilles Heel of Current-Generation Left Ventricular Assist Devices? Circ Heart Fail. 2015 Sep; 8(5):850-2. PMID: 26374917.
      View in: PubMed
    22. Pan X, Song YB, Liu GF, Hu YK, Ye XH, Cornwell WK, Prinzing A, Dong M, Cornelissen JH. Functional traits drive the contribution of solar radiation to leaf litter decomposition among multiple arid-zone species. Sci Rep. 2015 Aug 18; 5:13217. PMID: 26282711; PMCID: PMC4539537.
      View in: PubMed, PubMed Central
    23. Ackerly DD, Cornwell WK, Weiss SB, Flint LE, Flint AL. A Geographic Mosaic of Climate Change Impacts on Terrestrial Vegetation: Which Areas Are Most at Risk? PLoS One. 2015; 10(6):e0130629. PMID: 26115485.
      View in: PubMed
    24. Pennell MW, FitzJohn RG, Cornwell WK, Harmon LJ. Model Adequacy and the Macroevolution of Angiosperm Functional Traits. Am Nat. 2015 Aug; 186(2):E33-50. PMID: 26655160.
      View in: PubMed
    25. Werner GD, Cornwell WK, Cornelissen JH, Kiers ET. Evolutionary signals of symbiotic persistence in the legume-rhizobia mutualism. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10262-9. PMID: 26041807; PMCID: PMC4547229.
      View in: PubMed, PubMed Central
    26. Zanne AE, Tank DC, Cornwell WK, Eastman JM, Smith SA, FitzJohn RG, McGlinn DJ, O'Meara BC, Moles AT, Reich PB, Royer DL, Soltis DE, Stevens PF, Westoby M, Wright IJ, Aarssen L, Bertin RI, Calaminus A, Govaerts R, Hemmings F, Leishman MR, Oleksyn J, Soltis PS, Swenson NG, Warman L, Beaulieu JM. Corrigendum: Three keys to the radiation of angiosperms into freezing environments. Nature. 2015 May 21; 521(7552):380. PMID: 25993966.
      View in: PubMed
    27. Zanne AE, Tank DC, Cornwell WK, Eastman JM, Smith SA, FitzJohn RG, McGlinn DJ, O'Meara BC, Moles AT, Reich PB, Royer DL, Soltis DE, Stevens PF, Westoby M, Wright IJ, Aarssen L, Bertin RI, Calaminus A, Govaerts R, Hemmings F, Leishman MR, Oleksyn J, Soltis PS, Swenson NG, Warman L, Beaulieu JM. Zanne et al. reply. Nature. 2015 May 21; 521(7552):E6-7. PMID: 25993971.
      View in: PubMed
    28. Cornwell WK, Elvira A, van Kempen L, van Logtestijn RS, Aptroot A, Cornelissen JH. Flammability across the gymnosperm phylogeny: the importance of litter particle size. New Phytol. 2015 Apr; 206(2):672-81. PMID: 25675853.
      View in: PubMed
    29. Ye X, Tang S, Cornwell WK, Gao S, Huang Z, Dong M, Cornelissen JHC. Impact of land-use on carbon storage as dependent on soil texture: evidence from a desertified dryland using repeated paired sampling design. J Environ Manage. 2015 Mar 01; 150:489-498. PMID: 25560656.
      View in: PubMed
    30. Garg S, Ayers CR, Fitzsimmons C, Meyer D, Peltz M, Bethea B, Cornwell W, Araj F, Thibodeau J, Drazner MH. In-hospital cardiopulmonary arrests in patients with left ventricular assist devices. J Card Fail. 2014 Dec; 20(12):899-904. PMID: 25463416.
      View in: PubMed
    31. Cornwell WK, Levine BD. Patients with heart failure with reduced ejection fraction have exaggerated reductions in cerebral blood flow during upright posture. JACC Heart Fail. 2015 Feb; 3(2):176-9. PMID: 25543968.
      View in: PubMed
    32. Valladares F, Matesanz S, Guilhaumon F, Araújo MB, Balaguer L, Benito-Garzón M, Cornwell W, Gianoli E, van Kleunen M, Naya DE, Nicotra AB, Poorter H, Zavala MA. The effects of phenotypic plasticity and local adaptation on forecasts of species range shifts under climate change. Ecol Lett. 2014 Nov; 17(11):1351-64. PMID: 25205436.
      View in: PubMed
    33. Cornwell WK, Tarumi T, Aengevaeren VL, Ayers C, Divanji P, Fu Q, Palmer D, Drazner MH, Meyer DM, Bethea BT, Hastings JL, Fujimoto N, Shibata S, Zhang R, Markham DW, Levine BD. Effect of pulsatile and nonpulsatile flow on cerebral perfusion in patients with left ventricular assist devices. J Heart Lung Transplant. 2014 Dec; 33(12):1295-303. PMID: 25307621.
      View in: PubMed
    34. Pan X, Cornelissen JH, Zhao WW, Liu GF, Hu YK, Prinzing A, Dong M, Cornwell WK. Experimental evidence that the Ornstein-Uhlenbeck model best describes the evolution of leaf litter decomposability. Ecol Evol. 2014 Sep; 4(17):3339-49. PMID: 25535551; PMCID: PMC4228609.
      View in: PubMed, PubMed Central
    35. Levine BD, Cornwell WK, Drazner MH. Factors influencing the rate of flow through continuous-flow left ventricular assist devices at rest and with exercise. JACC Heart Fail. 2014 Aug; 2(4):331-4. PMID: 25023819.
      View in: PubMed
    36. Werner GD, Cornwell WK, Sprent JI, Kattge J, Kiers ET. A single evolutionary innovation drives the deep evolution of symbiotic N2-fixation in angiosperms. Nat Commun. 2014 Jun 10; 5:4087. PMID: 24912610; PMCID: PMC4059933.
      View in: PubMed, PubMed Central
    37. Krause S, van Bodegom PM, Cornwell WK, Bodelier PL. Weak phylogenetic signal in physiological traits of methane-oxidizing bacteria. J Evol Biol. 2014 Jun; 27(6):1240-7. PMID: 24797710.
      View in: PubMed
    38. Zanne AE, Tank DC, Cornwell WK, Eastman JM, Smith SA, FitzJohn RG, McGlinn DJ, O'Meara BC, Moles AT, Reich PB, Royer DL, Soltis DE, Stevens PF, Westoby M, Wright IJ, Aarssen L, Bertin RI, Calaminus A, Govaerts R, Hemmings F, Leishman MR, Oleksyn J, Soltis PS, Swenson NG, Warman L, Beaulieu JM. Three keys to the radiation of angiosperms into freezing environments. Nature. 2014 Feb 06; 506(7486):89-92. PMID: 24362564.
      View in: PubMed
    39. Temme AA, Cornwell WK, Cornelissen JH, Aerts R. Meta-analysis reveals profound responses of plant traits to glacial CO2 levels. Ecol Evol. 2013 Nov; 3(13):4525-35. PMID: 24340192; PMCID: PMC3856751.
      View in: PubMed, PubMed Central
    40. Funk JL, Cornwell WK. Leaf traits within communities: context may affect the mapping of traits to function. Ecology. 2013 Sep; 94(9):1893-7. PMID: 24279259.
      View in: PubMed
    41. Ellison S, Gabunia K, Kelemen SE, England RN, Scalia R, Richards JM, Orr AW, Orr W, Traylor JG, Rogers T, Cornwell W, Berglund LM, Goncalves I, Gomez MF, Autieri MV. Attenuation of experimental atherosclerosis by interleukin-19. Arterioscler Thromb Vasc Biol. 2013 Oct; 33(10):2316-24. PMID: 23950143; PMCID: PMC3950941.
      View in: PubMed, PubMed Central
    42. Kooyman RM, Zanne AE, Gallagher RV, Cornwell W, Rossetto M, O'Connor P, Parkes EA, Catterall CF, Laffan SW, Lusk CH. Effects of growth form and functional traits on response of woody plants to clearing and fragmentation of subtropical rainforest. Conserv Biol. 2013 Dec; 27(6):1468-77. PMID: 23869490.
      View in: PubMed
    43. Cornwell WK, Cornelissen JH. A broader perspective on plant domestication and nutrient and carbon cycling. New Phytol. 2013 Apr; 198(2):331-3. PMID: 23510185.
      View in: PubMed
    44. Moles AT, Peco B, Wallis IR, Foley WJ, Poore AG, Seabloom EW, Vesk PA, Bisigato AJ, Cella-Pizarro L, Clark CJ, Cohen PS, Cornwell WK, Edwards W, Ejrnaes R, Gonzales-Ojeda T, Graae BJ, Hay G, Lumbwe FC, Magaña-Rodríguez B, Moore BD, Peri PL, Poulsen JR, Stegen JC, Veldtman R, von Zeipel H, Andrew NR, Boulter SL, Borer ET, Cornelissen JH, Farji-Brener AG, DeGabriel JL, Jurado E, Kyhn LA, Low B, Mulder CP, Reardon-Smith K, Rodríguez-Velázquez J, De Fortier A, Zheng Z, Blendinger PG, Enquist BJ, Facelli JM, Knight T, Majer JD, Martínez-Ramos M, McQuillan P, Hui FK. Correlations between physical and chemical defences in plants: tradeoffs, syndromes, or just many different ways to skin a herbivorous cat? New Phytol. 2013 Apr; 198(1):252-63. PMID: 23316750.
      View in: PubMed
    45. van Altena C, van Logtestijn RS, Cornwell WK, Cornelissen JH. Species composition and fire: non-additive mixture effects on ground fuel flammability. Front Plant Sci. 2012; 3:63. PMID: 22639656; PMCID: PMC3355679.
      View in: PubMed, PubMed Central
    46. Westoby M, Cornwell WK, Falster DS. An evolutionary attractor model for sapwood cross section in relation to leaf area. J Theor Biol. 2012 Jun 21; 303:98-109. PMID: 22763134.
      View in: PubMed
    47. McLaughlin VV, Davis M, Cornwell W. Pulmonary arterial hypertension. Curr Probl Cardiol. 2011 Dec; 36(12):461-517. PMID: 22035608.
      View in: PubMed
    48. Cornwell WK, McLaughlin VV, Krishnan SM, Rubenfire M. Does the outcome justify an oral-first treatment strategy for management of pulmonary arterial hypertension? Chest. 2011 Sep; 140(3):697-705. PMID: 21622545.
      View in: PubMed
    49. Moles AT, Wallis IR, Foley WJ, Warton DI, Stegen JC, Bisigato AJ, Cella-Pizarro L, Clark CJ, Cohen PS, Cornwell WK, Edwards W, Ejrnaes R, Gonzales-Ojeda T, Graae BJ, Hay G, Lumbwe FC, Magaña-Rodríguez B, Moore BD, Peri PL, Poulsen JR, Veldtman R, von Zeipel H, Andrew NR, Boulter SL, Borer ET, Campón FF, Coll M, Farji-Brener AG, De Gabriel J, Jurado E, Kyhn LA, Low B, Mulder CP, Reardon-Smith K, Rodríguez-Velázquez J, Seabloom EW, Vesk PA, van Cauter A, Waldram MS, Zheng Z, Blendinger PG, Enquist BJ, Facelli JM, Knight T, Majer JD, Martínez-Ramos M, McQuillan P, Prior LD. Putting plant resistance traits on the map: a test of the idea that plants are better defended at lower latitudes. New Phytol. 2011 Aug; 191(3):777-88. PMID: 21539574.
      View in: PubMed
    50. Kembel SW, Cowan PD, Helmus MR, Cornwell WK, Morlon H, Ackerly DD, Blomberg SP, Webb CO. Picante: R tools for integrating phylogenies and ecology. Bioinformatics. 2010 Jun 01; 26(11):1463-4. PMID: 20395285.
      View in: PubMed
    51. Weedon JT, Cornwell WK, Cornelissen JH, Zanne AE, Wirth C, Coomes DA. Global meta-analysis of wood decomposition rates: a role for trait variation among tree species? Ecol Lett. 2009 Jan; 12(1):45-56. PMID: 19016827.
      View in: PubMed
    52. Cornwell WK, Cornelissen JH, Amatangelo K, Dorrepaal E, Eviner VT, Godoy O, Hobbie SE, Hoorens B, Kurokawa H, Pérez-Harguindeguy N, Quested HM, Santiago LS, Wardle DA, Wright IJ, Aerts R, Allison SD, van Bodegom P, Brovkin V, Chatain A, Callaghan TV, Díaz S, Garnier E, Gurvich DE, Kazakou E, Klein JA, Read J, Reich PB, Soudzilovskaia NA, Vaieretti MV, Westoby M. Plant species traits are the predominant control on litter decomposition rates within biomes worldwide. Ecol Lett. 2008 Oct; 11(10):1065-71. PMID: 18627410.
      View in: PubMed
    53. Kraft NJ, Cornwell WK, Webb CO, Ackerly DD. Trait evolution, community assembly, and the phylogenetic structure of ecological communities. Am Nat. 2007 Aug; 170(2):271-83. PMID: 17874377.
      View in: PubMed
    54. Ackerly DD, Cornwell WK. A trait-based approach to community assembly: partitioning of species trait values into within- and among-community components. Ecol Lett. 2007 Feb; 10(2):135-45. PMID: 17257101.
      View in: PubMed
    55. Cornwell WK, Schwilk LD, Ackerly DD. A trait-based test for habitat filtering: convex hull volume. Ecology. 2006 Jun; 87(6):1465-71. PMID: 16869422.
      View in: PubMed
    56. Preston KA, Cornwell WK, Denoyer JL. Wood density and vessel traits as distinct correlates of ecological strategy in 51 California coast range angiosperms. New Phytol. 2006; 170(4):807-18. PMID: 16684240.
      View in: PubMed
    57. Tong GC, Cornwell WK, Means GE. Reactions of acrylamide with glutathione and serum albumin. Toxicol Lett. 2004 Mar 01; 147(2):127-31. PMID: 14757316.
      View in: PubMed
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