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Keith Andrew Koch

TitleAsst Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG. ASK1 contributes to fibrosis and dysfunction in models of kidney disease. J Clin Invest. 2018 Oct 01; 128(10):4485-4500. PMID: 30024858.
      View in: PubMed
    2. Stratton MS, Koch KA, McKinsey TA. p38a: A Profibrotic Signaling Nexus. Circulation. 2017 08 08; 136(6):562-565. PMID: 28784825.
      View in: PubMed
    3. Schuetze KB, Koch KA, McKinsey TA. The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases. Future Med Chem. 2016 09; 8(13):1533-6. PMID: 27556930.
      View in: PubMed
    4. Huynh QK, Wise SJ, Koch KA, Castonguay LA, Reid BG, Pagratis EE, Koditek D, Glascock CB, Pitts KR, Turner BA, Liu X, Hung M, Han B, Pagratis N. Screening and identification of a novel class of TGF-ß type 1 receptor kinase inhibitor. J Biomol Screen. 2011 Aug; 16(7):724-33. PMID: 21521800.
      View in: PubMed
    5. Gamber GG, Meredith E, Zhu Q, Yan W, Rao C, Capparelli M, Burgis R, Enyedy I, Zhang JH, Soldermann N, Beattie K, Rozhitskaya O, Koch KA, Pagratis N, Hosagrahara V, Vega RB, McKinsey TA, Monovich L. 3,5-diarylazoles as novel and selective inhibitors of protein kinase D. Bioorg Med Chem Lett. 2011 Mar 01; 21(5):1447-51. PMID: 21300545.
      View in: PubMed
    6. Meredith EL, Beattie K, Burgis R, Capparelli M, Chapo J, Dipietro L, Gamber G, Enyedy I, Hood DB, Hosagrahara V, Jewell C, Koch KA, Lee W, Lemon DD, McKinsey TA, Miranda K, Pagratis N, Phan D, Plato C, Rao C, Rozhitskaya O, Soldermann N, Springer C, van Eis M, Vega RB, Yan W, Zhu Q, Monovich LG. Identification of potent and selective amidobipyridyl inhibitors of protein kinase D. J Med Chem. 2010 Aug 12; 53(15):5422-38. PMID: 20684592.
      View in: PubMed
    7. Monovich L, Vega RB, Meredith E, Miranda K, Rao C, Capparelli M, Lemon DD, Phan D, Koch KA, Chapo JA, Hood DB, McKinsey TA. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase. FEBS Lett. 2010 Feb 05; 584(3):631-7. PMID: 20018189.
      View in: PubMed
    8. Monovich L, Koch KA, Burgis R, Osimboni E, Mann T, Wall D, Gao J, Feng Y, Vega RB, Turner BA, Hood DB, Law A, Papst PJ, Koditek D, Chapo JA, Reid BG, Melvin LS, Pagratis NC, McKinsey TA. Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1. Biochim Biophys Acta. 2009 May; 1789(5):422-31. PMID: 19414071.
      View in: PubMed
    9. Fornarotto M, Xiao L, Hou Y, Koch KA, Chang E, O'Malley RM, Black TA, Cable MB, Walker SS. Sphingolipid biosynthesis in pathogenic fungi: identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus. Biochim Biophys Acta. 2006 Jan; 1761(1):52-63. PMID: 16431155.
      View in: PubMed
    10. Deu E, Koch KA, Kirsch JF. The role of the conserved Lys68*:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: multiple forced covariant amino acid substitutions in natural variants. Protein Sci. 2002 May; 11(5):1062-73. PMID: 11967363.
      View in: PubMed
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