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Toby Charles Cornish

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Pathology
ORCID ORCID Icon0000-0002-1902-2109 Additional info

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    R21CA237493     (XING, FUYONG)Apr 2, 2019 - Mar 31, 2021
    NIH
    Development and Dissemination of KiNet: A Novel Imaging Informatics Tool for Gastrointestinal and Pancreatic Neuroendocrine Tumors
    Role: Co-Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Xing F, Cornish TC, Bennett TD, Ghosh D. Bidirectional Mapping-Based Domain Adaptation for Nucleus Detection in Cross-Modality Microscopy Images. IEEE Trans Med Imaging. 2021 10; 40(10):2880-2896. PMID: 33284750.
      View in: PubMed
    2. Roth CJ, Clunie DA, Vining DJ, Berkowitz SJ, Berlin A, Bissonnette JP, Clark SD, Cornish TC, Eid M, Gaskin CM, Goel AK, Jacobs GC, Kwan D, Luviano DM, McBee MP, Miller K, Hafiz AM, Obcemea C, Parwani AV, Rotemberg V, Silver EL, Storm ES, Tcheng JE, Thullner KS, Folio LR. Multispecialty Enterprise Imaging Workgroup Consensus on Interactive Multimedia Reporting Current State and Road to the Future: HIMSS-SIIM Collaborative White Paper. J Digit Imaging. 2021 06; 34(3):495-522. PMID: 34131793.
      View in: PubMed
    3. Cornish TC. Artificial intelligence for automating the measurement of histologic image biomarkers. J Clin Invest. 2021 04 15; 131(8). PMID: 33855974.
      View in: PubMed
    4. Cornish TC, Kricka LJ, Park JY. A Biopython-based method for comprehensively searching for eponyms in Pubmed. MethodsX. 2021; 8:101264. PMID: 34434786.
      View in: PubMed
    5. Kricka LJ, Cornish TC, Park JY. Eponyms in clinical chemistry. Clin Chim Acta. 2021 Jan; 512:28-32. PMID: 33242467.
      View in: PubMed
    6. Abel JT, Ouillette P, Williams CL, Blau J, Cheng J, Yao K, Lee WY, Cornish TC, Balis UGJ, McClintock DS. Display Characteristics and Their Impact on Digital Pathology: A Current Review of Pathologists' Future "Microscope". J Pathol Inform. 2020; 11:23. PMID: 33042602.
      View in: PubMed
    7. Kolb JM, Aihara H, Wani S, Cornish TC, Hammad H. Severe submucosal fibrosis and granuloma complicating endoscopic submucosal dissection: unintended consequences of a lifting agent (with video). Gastrointest Endosc. 2021 02; 93(2):524-526. PMID: 32763243.
      View in: PubMed
    8. Cornish TC. Clinical Application of Image Analysis in Pathology. Adv Anat Pathol. 2020 Jul; 27(4):227-235. PMID: 32467397.
      View in: PubMed
    9. Zhang X, Cornish TC, Yang L, Bennett TD, Ghosh D, Xing F. Generative Adversarial Domain Adaptation for Nucleus Quantification in Images of Tissue Immunohistochemically Stained for Ki-67. JCO Clin Cancer Inform. 2020 07; 4:666-679. PMID: 32730116.
      View in: PubMed
    10. Westbrook LM, Henn PA, Cornish TC. Lifting Agent Granuloma. Am J Clin Pathol. 2020 04 15; 153(5):630-638. PMID: 31875886.
      View in: PubMed
    11. Xing F, Cornish TC, Bennett T, Ghosh D, Yang L. Pixel-to-Pixel Learning With Weak Supervision for Single-Stage Nucleus Recognition in Ki67 Images. IEEE Trans Biomed Eng. 2019 11; 66(11):3088-3097. PMID: 30802845.
      View in: PubMed
    12. Evans AJ, Bauer TW, Bui MM, Cornish TC, Duncan H, Glassy EF, Hipp J, McGee RS, Murphy D, Myers C, O'Neill DG, Parwani AV, Rampy BA, Salama ME, Pantanowitz L. US Food and Drug Administration Approval of Whole Slide Imaging for Primary Diagnosis: A Key Milestone Is Reached and New Questions Are Raised. Arch Pathol Lab Med. 2018 11; 142(11):1383-1387. PMID: 29708429.
      View in: PubMed
    13. Robertson SA, Cimino-Mathews A, Cornish TC. HER2 Status in Gastroesophageal Adenocarcinomas: Correlation Between Immunohistochemistry and Fluorescence In Situ Hybridization Methodologies. Appl Immunohistochem Mol Morphol. 2018 Jan; 26(1):35-39. PMID: 27153447.
      View in: PubMed
    14. Baena-Del Valle JA, Zheng Q, Hicks JL, Fedor H, Trock BJ, Morrissey C, Corey E, Cornish TC, Sfanos KS, De Marzo AM. Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides. Am J Clin Pathol. 2017 Nov 02; 148(5):398-415. PMID: 29106457.
      View in: PubMed
    15. Yanik EL, Kaunitz GJ, Cottrell TR, Succaria F, McMiller TL, Ascierto ML, Esandrio J, Xu H, Ogurtsova A, Cornish T, Lipson EJ, Topalian SL, Engels EA, Taube JM. Association of HIV Status With Local Immune Response to Anal Squamous Cell Carcinoma: Implications for Immunotherapy. JAMA Oncol. 2017 Jul 01; 3(7):974-978. PMID: 28334399.
      View in: PubMed
    16. Park JY, Cornish TC, Hogarth M, Jackson BR, Rosati KB. Patient Privacy and Clinical Laboratory Data. Clin Chem. 2017 08; 63(8):1321-1325. PMID: 28588122.
      View in: PubMed
    17. Palchaudhuri S, Cornish T, Inouye C, Nimgaonkar A. Tough to Swallow: Esophageal Food Impaction from Esophageal Amyloidosis. Dig Dis Sci. 2017 05; 62(5):1165-1167. PMID: 26961786.
      View in: PubMed
    18. Sunshine JC, Nguyen PL, Kaunitz GJ, Cottrell TR, Berry S, Esandrio J, Xu H, Ogurtsova A, Bleich KB, Cornish TC, Lipson EJ, Anders RA, Taube JM. PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison. Clin Cancer Res. 2017 Aug 15; 23(16):4938-4944. PMID: 28428193.
      View in: PubMed
    19. Hempel HA, Cuka NS, Kulac I, Barber JR, Cornish TC, Platz EA, De Marzo AM, Sfanos KS. Low Intratumoral Mast Cells Are Associated With a Higher Risk of Prostate Cancer Recurrence. Prostate. 2017 03; 77(4):412-424. PMID: 27868214.
      View in: PubMed
    20. Zampella JG, Rodic N, Yang WR, Huang CR, Welch J, Gnanakkan VP, Cornish TC, Boeke JD, Burns KH. A map of mobile DNA insertions in the NCI-60 human cancer cell panel. Mob DNA. 2016; 7:20. PMID: 27807467.
      View in: PubMed
    21. Aiello NM, Bajor DL, Norgard RJ, Sahmoud A, Bhagwat N, Pham MN, Cornish TC, Iacobuzio-Donahue CA, Vonderheide RH, Stanger BZ. Metastatic progression is associated with dynamic changes in the local microenvironment. Nat Commun. 2016 09 15; 7:12819. PMID: 27628423.
      View in: PubMed
    22. Duran R, Mirpour S, Pekurovsky V, Ganapathy-Kanniappan S, Brayton CF, Cornish TC, Gorodetski B, Reyes J, Chapiro J, Schernthaner RE, Frangakis C, Lin M, Sun JD, Hart CP, Geschwind JF. Preclinical Benefit of Hypoxia-Activated Intra-arterial Therapy with Evofosfamide in Liver Cancer. Clin Cancer Res. 2017 Jan 15; 23(2):536-548. PMID: 27440271.
      View in: PubMed
    23. Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodic N. Genome-wide characterization of human L1 antisense promoter-driven transcripts. BMC Genomics. 2016 06 14; 17:463. PMID: 27301971.
      View in: PubMed
    24. Sue PK, Salazar-Austin NM, McDonald OG, Rishi A, Cornish TC, Arav-Boger R. Cytomegalovirus Enterocolitis in Immunocompetent Young Children: A Report of Two Cases and Review of the Literature. Pediatr Infect Dis J. 2016 May; 35(5):573-6. PMID: 26862673.
      View in: PubMed
    25. Anene DF, Rosenberg AZ, Kleiner DE, Cornish TC, Halushka MK. Utilization of HPASubC for the Identification of Sinusoid-Specific Proteins in the Liver. J Proteome Res. 2016 05 06; 15(5):1623-9. PMID: 27005832.
      View in: PubMed
    26. Thompson ED, Zahurak M, Murphy A, Cornish T, Cuka N, Abdelfatah E, Yang S, Duncan M, Ahuja N, Taube JM, Anders RA, Kelly RJ. Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma. Gut. 2017 05; 66(5):794-801. PMID: 26801886.
      View in: PubMed
    27. Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK. miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy. PLoS One. 2015; 10(11):e0143066. PMID: 26571139.
      View in: PubMed
    28. Cimino-Mathews A, Thompson E, Taube JM, Ye X, Lu Y, Meeker A, Xu H, Sharma R, Lecksell K, Cornish TC, Cuka N, Argani P, Emens LA. PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas. Hum Pathol. 2016 Jan; 47(1):52-63. PMID: 26527522.
      View in: PubMed
    29. Cornish TC, Chakravarti A, Kapoor A, Halushka MK. HPASubC: A suite of tools for user subclassification of human protein atlas tissue images. J Pathol Inform. 2015; 6:36. PMID: 26167380.
      View in: PubMed
    30. Rowe SP, Gage KL, Faraj SF, Macura KJ, Cornish TC, Gonzalez-Roibon N, Guner G, Munari E, Partin AW, Pavlovich CP, Han M, Carter HB, Bivalacqua TJ, Blackford A, Holt D, Dannals RF, Netto GJ, Lodge MA, Mease RC, Pomper MG, Cho SY. ¹8F-DCFBC PET/CT for PSMA-Based Detection and Characterization of Primary Prostate Cancer. J Nucl Med. 2015 Jul; 56(7):1003-1010. PMID: 26069305.
      View in: PubMed
    31. Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz LA. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. N Engl J Med. 2015 Jun 25; 372(26):2509-20. PMID: 26028255.
      View in: PubMed
    32. Shi C, Gonzalez RS, Zhao Z, Koyama T, Cornish TC, Hande KR, Walker R, Sandler M, Berlin J, Liu EH. Liver metastases of small intestine neuroendocrine tumors: Ki-67 heterogeneity and World Health Organization grade discordance with primary tumors. Am J Clin Pathol. 2015 Mar; 143(3):398-404. PMID: 25696798.
      View in: PubMed
    33. Chapiro J, Wood LD, Lin M, Duran R, Cornish T, Lesage D, Charu V, Schernthaner R, Wang Z, Tacher V, Savic LJ, Kamel IR, Geschwind JF. Radiologic-pathologic analysis of contrast-enhanced and diffusion-weighted MR imaging in patients with HCC after TACE: diagnostic accuracy of 3D quantitative image analysis. Radiology. 2014 Dec; 273(3):746-58. PMID: 25028783.
      View in: PubMed
    34. Wu YE, Baras A, Cornish T, Riedel S, Burton EC. Fatal spontaneous Clostridium septicum gas gangrene: a possible association with iatrogenic gastric acid suppression. Arch Pathol Lab Med. 2014 Jun; 138(6):837-41. PMID: 24878026.
      View in: PubMed
    35. Kent OA, McCall MN, Cornish TC, Halushka MK. Lessons from miR-143/145: the importance of cell-type localization of miRNAs. Nucleic Acids Res. 2014 Jul; 42(12):7528-38. PMID: 24875473.
      View in: PubMed
    36. Olson MT, Novak A, Boonyaarunnate T, Trotter J, Sachs S, Kelly D, Ford S, Cornish TC, Toll A, Tatsas AD, Maleki Z, Erozan YS, Rosenthal DL. Reproducibility of the Johns Hopkins Hospital template for urologic cytology samples. J Am Soc Cytopathol. 2014 May - Jun; 3(3):156-164. PMID: 31051740.
      View in: PubMed
    37. Haider BA, Baras AS, McCall MN, Hertel JA, Cornish TC, Halushka MK. A critical evaluation of microRNA biomarkers in non-neoplastic disease. PLoS One. 2014; 9(2):e89565. PMID: 24586876.
      View in: PubMed
    38. Ellison TA, Wolfgang CL, Shi C, Cameron JL, Murakami P, Mun LJ, Singhi AD, Cornish TC, Olino K, Meriden Z, Choti M, Diaz LA, Pawlik TM, Schulick RD, Hruban RH, Edil BH. A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram. Ann Surg. 2014 Feb; 259(2):204-12. PMID: 23673766.
      View in: PubMed
    39. Cornish TC, McClintock DS. Diagnostic Histopathology. Medicolegal and regulatory aspects of whole slide imaging-based telepathology. 2014; 12(20):475-481.
    40. McCall CM, Shi C, Cornish TC, Klimstra DS, Tang LH, Basturk O, Mun LJ, Ellison TA, Wolfgang CL, Choti MA, Schulick RD, Edil BH, Hruban RH. Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate. Am J Surg Pathol. 2013 Nov; 37(11):1671-7. PMID: 24121170.
      View in: PubMed
    41. Rodic N, Zampella JG, Cornish TC, Wheelan SJ, Burns KH. Translocation junctions in TCF3-PBX1 acute lymphoblastic leukemia/lymphoma cluster near transposable elements. Mob DNA. 2013 Oct 17; 4(1):22. PMID: 24135088.
      View in: PubMed
    42. Samols MA, Smith NE, Gerber JM, Vuica-Ross M, Gocke CD, Burns KH, Borowitz MJ, Cornish TC, Duffield AS. Software-automated counting of Ki-67 proliferation index correlates with pathologic grade and disease progression of follicular lymphomas. Am J Clin Pathol. 2013 Oct; 140(4):579-87. PMID: 24045557.
      View in: PubMed
    43. Pavlovich CP, Cornish TC, Mullins JK, Fradin J, Mettee LZ, Connor JT, Reese AC, Askin FB, Luck R, Epstein JI, Burke HB. High-resolution transrectal ultrasound: pilot study of a novel technique for imaging clinically localized prostate cancer. Urol Oncol. 2014 Jan; 32(1):34.e27-32. PMID: 23558161.
      View in: PubMed
    44. Tobian AA, Grabowski MK, Kigozi G, Redd AD, Eaton KP, Serwadda D, Cornish TC, Nalugoda F, Watya S, Buwembo D, Nkale J, Wawer MJ, Quinn TC, Gray RH. Human papillomavirus clearance among males is associated with HIV acquisition and increased dendritic cell density in the foreskin. J Infect Dis. 2013 Jun 01; 207(11):1713-22. PMID: 23345339.
      View in: PubMed
    45. Bai H, Zhang N, Xu Y, Chen Q, Khan M, Potter JJ, Nayar SK, Cornish T, Alpini G, Bronk S, Pan D, Anders RA. Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology. 2012 Sep; 56(3):1097-107. PMID: 22886419.
      View in: PubMed
    46. Cornish TC, Swapp RE, Kaplan KJ. Whole-slide imaging: routine pathologic diagnosis. Adv Anat Pathol. 2012 May; 19(3):152-9. PMID: 22498580.
      View in: PubMed
    47. Kim B, Barker NJ, Hruban RH, Sandone C, Cornish TC. The Johns Hopkins Atlas of Pancreatic Pathology: Developing an Interactive Atlas and Teaching Algorithm for the Apple iPad. The Journal of Biocommunication. 2012; 1(38):4-10.
    48. Meriden Z, Shi C, Edil BH, Ellison T, Wolfgang CL, Cornish TC, Schulick RD, Hruban RH. Hyaline globules in neuroendocrine and solid-pseudopapillary neoplasms of the pancreas: a clue to the diagnosis. Am J Surg Pathol. 2011 Jul; 35(7):981-8. PMID: 21677537.
      View in: PubMed
    49. Bisht S, Khan MA, Bekhit M, Bai H, Cornish T, Mizuma M, Rudek MA, Zhao M, Maitra A, Ray B, Lahiri D, Maitra A, Anders RA. A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation. Lab Invest. 2011 Sep; 91(9):1383-95. PMID: 21691262.
      View in: PubMed
    50. Cornish TC, Hruban RH. Pancreatic Intraepithelial Neoplasia. Surg Pathol Clin. 2011 Jun; 4(2):523-35. PMID: 26837486.
      View in: PubMed
    51. Johnson KE, Redd AD, Quinn TC, Collinson-Streng AN, Cornish T, Kong X, Sharma R, Tobian AA, Tsai B, Sherman ME, Kigozi G, Serwadda D, Wawer MJ, Gray RH. Effects of HIV-1 and herpes simplex virus type 2 infection on lymphocyte and dendritic cell density in adult foreskins from Rakai, Uganda. J Infect Dis. 2011 Mar 01; 203(5):602-9. PMID: 21220779.
      View in: PubMed
    52. Lam-Himlin D, Park JY, Cornish TC, Shi C, Montgomery E. Morphologic characterization of syndromic gastric polyps. Am J Surg Pathol. 2010 Nov; 34(11):1656-62. PMID: 20924281.
      View in: PubMed
    53. Park JY, Cornish TC, Lam-Himlin D, Shi C, Montgomery E. Gastric lesions in patients with autoimmune metaplastic atrophic gastritis (AMAG) in a tertiary care setting. Am J Surg Pathol. 2010 Nov; 34(11):1591-8. PMID: 20975338.
      View in: PubMed
    54. Shi C, Scudiere JR, Cornish TC, Lam-Himlin D, Park JY, Fox MR, Montgomery EA. Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. Am J Surg Pathol. 2010 Sep; 34(9):1344-50. PMID: 20697252.
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    55. Cornish TC, Halushka MK. Color deconvolution for the analysis of tissue microarrays. Anal Quant Cytol Histol. 2009 Oct; 31(5):304-12. PMID: 20701098.
      View in: PubMed
    56. Selvin E, Najjar SS, Cornish TC, Halushka MK. A comprehensive histopathological evaluation of vascular medial fibrosis: insights into the pathophysiology of arterial stiffening. Atherosclerosis. 2010 Jan; 208(1):69-74. PMID: 19632677.
      View in: PubMed
    57. Hillel AT, Taube JM, Cornish TC, Sharma B, Halushka M, McCarthy EF, Hutchins GM, Elisseeff JH. Characterization of human mesenchymal stem cell-engineered cartilage: analysis of its ultrastructure, cell density and chondrocyte phenotype compared to native adult and fetal cartilage. Cells Tissues Organs. 2010; 191(1):12-20. PMID: 19546516.
      View in: PubMed
    58. Cornish TC, Bagnasco SM, Macgregor AM, Lu J, Selvin E, Halushka MK. Glomerular protein levels of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 are lower in diabetic subjects. J Histochem Cytochem. 2009 Nov; 57(11):995-1001. PMID: 19506087.
      View in: PubMed
    59. Halushka MK, Selvin E, Lu J, Macgregor AM, Cornish TC. Use of human vascular tissue microarrays for measurement of advanced glycation endproducts. J Histochem Cytochem. 2009 Jun; 57(6):559-66. PMID: 19223295.
      View in: PubMed
    60. Halushka MK, Cornish TC, Lu J, Selvin S, Selvin E. Creation, validation, and quantitative analysis of protein expression in vascular tissue microarrays. Cardiovasc Pathol. 2010 May-Jun; 19(3):136-46. PMID: 19211265.
      View in: PubMed
    61. Yegnasubramanian S, Haffner MC, Zhang Y, Gurel B, Cornish TC, Wu Z, Irizarry RA, Morgan J, Hicks J, DeWeese TL, Isaacs WB, Bova GS, De Marzo AM, Nelson WG. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res. 2008 Nov 01; 68(21):8954-67. PMID: 18974140.
      View in: PubMed
    62. Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol. 2008 Sep; 21(9):1156-67. PMID: 18567993.
      View in: PubMed
    63. Cornish T, Branch DW, Wheeler BC, Campanelli JT. Microcontact printing: a versatile technique for the study of synaptogenic molecules. Mol Cell Neurosci. 2002 May; 20(1):140-53. PMID: 12056845.
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    64. Cornish T, Chi J, Johnson S, Lu Y, Campanelli JT. Globular domains of agrin are functional units that collaborate to induce acetylcholine receptor clustering. J Cell Sci. 1999 Apr; 112 ( Pt 8):1213-23. PMID: 10085256.
      View in: PubMed
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