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Willi K Born

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-IMM MICRO GENERAL OPER

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    R01AI027903     (BORN, WILLI K)Apr 1, 1989 - Mar 31, 1997
    NIH/NIAID
    REPERTOIRE/SPECIFICITY/FUNCTION OF GAMMA/DELTA T-CELLS
    Role: Principal Investigator
    R01AI040611     (BORN, WILLI K)Jul 1, 1997 - Sep 29, 2000
    NIH/NIAID
    GAMMA DELTA T CELL RESPONSES TO POLYVALENT ANTIGENS
    Role: Principal Investigator
    R01HL065410     (BORN, WILLI K)Sep 30, 2000 - Aug 31, 2009
    NIH/NHLBI
    Airway Function-Role of gamma/delta T Cells
    Role: Principal Investigator
    R21AI095765     (BORN, WILLI K)Feb 7, 2012 - Jan 31, 2014
    NIH/NIAID
    Inhalation Tolerance, IgE and gamma/delta T cells
    Role: Principal Investigator
    R21AI122135     (BORN, WILLI K)Jul 1, 2016 - Jun 30, 2018
    NIH/NIAID
    Control of IL-4 by gamma/delta T Cells
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Born W, Zúñiga-Pflücker JC, Edelblum K, Kabelitz D, Hayday A, Witherden D, Jameson J. Wendy Havran: Scientist, mentor, advocate. Immunol Rev. 2020 Oct 16. PMID: 33063340.
      View in: PubMed
    2. O'Brien RL, Born WK. Two functionally distinct subsets of IL-17 producing ?d T cells. Immunol Rev. 2020 Jul 22. PMID: 32700361.
      View in: PubMed
    3. White J, O'Brien RL, Born WK. BW5147 and Derivatives for the Study of T Cells and their Antigen Receptors. Arch Immunol Ther Exp (Warsz). 2020 May 18; 68(3):15. PMID: 32419056.
      View in: PubMed
    4. Phalke SP, Huang Y, Rubtsova K, Getahun A, Sun D, Reinhardt RL, O'Brien RL, Born WK. ?d T cells shape memory-phenotype aß T cell populations in non-immunized mice. PLoS One. 2019; 14(6):e0218827. PMID: 31237933.
      View in: PubMed
    5. Liang D, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Correction: High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of ?d T cells in the autoimmune responses of EAU. PLoS One. 2018; 13(11):e0207546. PMID: 30408117.
      View in: PubMed
    6. Li X, Liang D, Shao H, Born WK, Kaplan HJ, Sun D. Adenosine receptor activation in the Th17 autoimmune responses of experimental autoimmune uveitis. Cell Immunol. 2019 05; 339:24-28. PMID: 30249343.
      View in: PubMed
    7. Liang D, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of ?d T cells in the autoimmune responses of EAU. PLoS One. 2018; 13(6):e0199601. PMID: 29928041.
      View in: PubMed
    8. Liang D, Woo JI, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Ability of ?d T cells to modulate the Foxp3 T cell response is dependent on adenosine. PLoS One. 2018; 13(5):e0197189. PMID: 29771938.
      View in: PubMed
    9. Zeng W, O'Brien RL, Born WK, Huang Y. Characterization of Mouse ?d T Cell Subsets in the Setting of Type-2 Immunity. Methods Mol Biol. 2018; 1799:135-151. PMID: 29956150.
      View in: PubMed
    10. Liang D, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Connection between ?d T-cell- and Adenosine- Mediated Immune Regulation in the Pathogenesis of Experimental Autoimmune Uveitis. Crit Rev Immunol. 2018; 38(3):233-243. PMID: 30004859.
      View in: PubMed
    11. Born WK, Huang Y, Reinhardt RL, Huang H, Sun D, O'Brien RL. ?d T Cells and B Cells. Adv Immunol. 2017; 134:1-45. PMID: 28413020.
      View in: PubMed
    12. Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine aß T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. J Immunol. 2016 11 01; 197(9):3437-3443. PMID: 27824590.
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    13. Liang D, Zuo A, Zhao R, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Correction: CD73 Expressed on ?d T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis. PLoS One. 2016; 11(10):e0164502. PMID: 27701472.
      View in: PubMed
    14. Born WK, Huang Y, Zeng W, Torres RM, O'Brien RL. A Special Connection between ?d T Cells and Natural Antibodies? Arch Immunol Ther Exp (Warsz). 2016 Dec; 64(6):455-462. PMID: 27235134.
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    15. Born WK, O'Brien RL. Discovery of the ?d TCR: Act II. J Immunol. 2016 05 01; 196(9):3507-8. PMID: 27183646.
      View in: PubMed
    16. Liang D, Zuo A, Zhao R, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. CD73 Expressed on ?d T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis. PLoS One. 2016; 11(2):e0150078. PMID: 26919582.
      View in: PubMed
    17. Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, Born WK. ?d T Cells Shape Preimmune Peripheral B Cell Populations. J Immunol. 2016 Jan 01; 196(1):217-31. PMID: 26582947.
      View in: PubMed
    18. Huang Y, Yang Z, Huang C, McGowan J, Casper T, Sun D, Born WK, O'Brien RL. ?d T Cell-Dependent Regulatory T Cells Prevent the Development of Autoimmune Keratitis. J Immunol. 2015 Dec 15; 195(12):5572-81. PMID: 26566677.
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    19. Huang Y, Yang Z, McGowan J, Huang H, O'Brien RL, Born WK. Regulation of IgE Responses by ?d T Cells. Curr Allergy Asthma Rep. 2015 Apr; 15(4):13. PMID: 26130476.
      View in: PubMed
    20. O'Brien RL, Born WK. Dermal ?d T cells--What have we learned? Cell Immunol. 2015 Jul; 296(1):62-9. PMID: 25649119.
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    21. Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK. ?d T cells affect IL-4 production and B-cell tolerance. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):E39-48. PMID: 25535377.
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    22. Kedl RM, Wysocki LJ, Janssen WJ, Born WK, Rosenbaum MD, Granowski J, Kench JA, Fong DL, Switzer LA, Cruse M, Huang H, Jakubzick CV, Kosmider B, Takeda K, Stranova TJ, Klumm RC, Delgado C, Tummala S, De Langhe S, Cambier J, Haskins K, Lenz LL, Curran-Everett D. General parity between trio and pairwise breeding of laboratory mice in static caging. J Immunol. 2014 Nov 15; 193(10):4757-60. PMID: 25381356.
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    23. Zhang J, Wang J, Pang L, Xie G, Welte T, Saxena V, Wicker J, Mann B, Soong L, Barrett A, Born W, O'Brien R, Wang T. The co-stimulatory effects of MyD88-dependent Toll-like receptor signaling on activation of murine ?d T cells. PLoS One. 2014; 9(9):e108156. PMID: 25232836.
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    24. Aydintug MK, Zhang L, Wang C, Liang D, Wands JM, Michels AW, Hirsch B, Day BJ, Zhang G, Sun D, Eisenbarth GS, O'Brien RL, Born WK. ?d T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation. Mol Immunol. 2014 Aug; 60(2):116-28. PMID: 24853397.
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    25. Liang D, Zuo A, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. IL-23 receptor expression on ?d T cells correlates with their enhancing or suppressive effects on autoreactive T cells in experimental autoimmune uveitis. J Immunol. 2013 Aug 01; 191(3):1118-25. PMID: 23797670.
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    26. Liang D, Zuo A, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Retinoic acid inhibits CD25+ dendritic cell expansion and ?d T-cell activation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2013 May 01; 54(5):3493-503. PMID: 23611991.
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    27. Roark CL, Huang Y, Jin N, Aydintug MK, Casper T, Sun D, Born WK, O'Brien RL. A canonical V?4Vd4+ ?d T cell population with distinct stimulation requirements which promotes the Th17 response. Immunol Res. 2013 Mar; 55(1-3):217-30. PMID: 22961659.
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    28. Huang Y, Aydintug MK, Loomis J, Macleod MK, McKee AS, Kirchenbaum G, Jakubzick CV, Kedl RM, Sun D, Jacobelli J, O'Brien RL, Born WK. Antigen-specific regulation of IgE antibodies by non-antigen-specific ?d T cells. J Immunol. 2013 Feb 01; 190(3):913-21. PMID: 23275606.
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    29. Born WK, Kemal Aydintug M, O'Brien RL. Diversity of ?d T-cell antigens. Cell Mol Immunol. 2013 Jan; 10(1):13-20. PMID: 23085946.
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    30. Liang D, Zuo A, Shao H, Born WK, O'Brien RL, Kaplan HJ, Sun D. Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis. J Immunol. 2012 Jun 01; 188(11):5785-91. PMID: 22539790.
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    31. Nian H, Liang D, Zuo A, Wei R, Shao H, Born WK, Kaplan HJ, Sun D. Characterization of autoreactive and bystander IL-17+ T cells induced in immunized C57BL/6 mice. Invest Ophthalmol Vis Sci. 2012 Feb; 53(2):897-905. PMID: 22247477.
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    32. Zuo A, Liang D, Shao H, Born WK, Kaplan HJ, Sun D. In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via ?d T cell activation. Mol Immunol. 2012 Mar; 50(3):125-33. PMID: 22301006.
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    33. O'Brien RL, Chain JL, Aydintug MK, Bohrer-Kunter D, Huang Y, Hardy IR, Cambier JC, Lahmers K, Nuhsbaum T, Davidson R, Sun D, Born WK. aß TCR? T cells, but not B cells, promote autoimmune keratitis in b10 mice lacking ?d T cells. Invest Ophthalmol Vis Sci. 2012 Jan 25; 53(1):301-8. PMID: 22199243.
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    34. Welte T, Aronson J, Gong B, Rachamallu A, Mendell N, Tesh R, Paessler S, Born WK, O'Brien RL, Wang T. V?4+ T cells regulate host immune response to West Nile virus infection. FEMS Immunol Med Microbiol. 2011 Nov; 63(2):183-92. PMID: 22077221.
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    35. Hao J, Dong S, Xia S, He W, Jia H, Zhang S, Wei J, O'Brien RL, Born WK, Wu Z, Wang P, Han J, Hong Z, Zhao L, Yin Z. Regulatory role of V?1 ?d T cells in tumor immunity through IL-4 production. J Immunol. 2011 Nov 15; 187(10):4979-86. PMID: 21987661.
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    36. Nian H, Shao H, O'Brien RL, Born WK, Kaplan HJ, Sun D. Activated gammadelta T cells promote the activation of uveitogenic T cells and exacerbate EAU development. Invest Ophthalmol Vis Sci. 2011 Jul 29; 52(8):5920-7. PMID: 21296823.
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    37. Born WK, Zhang L, Nakayama M, Jin N, Chain JL, Huang Y, Aydintug MK, O'Brien RL. Peptide antigens for gamma/delta T cells. Cell Mol Life Sci. 2011 Jul; 68(14):2335-43. PMID: 21553233.
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    38. Born WK, O'Brien RL. ?d T cells develop, respond and survive - with a little help from CD27. Eur J Immunol. 2011 Jan; 41(1):26-8. PMID: 21182073.
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    39. Simonian PL, Wehrmann F, Roark CL, Born WK, O'Brien RL, Fontenot AP. ?d T cells protect against lung fibrosis via IL-22. J Exp Med. 2010 Sep 27; 207(10):2239-53. PMID: 20855496.
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    40. Bonneville M, O'Brien RL, Born WK. Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat Rev Immunol. 2010 Jul; 10(7):467-78. PMID: 20539306.
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    41. He W, Hao J, Dong S, Gao Y, Tao J, Chi H, Flavell R, O'Brien RL, Born WK, Craft J, Han J, Wang P, Zhao L, Wu J, Yin Z. Naturally activated V gamma 4 gamma delta T cells play a protective role in tumor immunity through expression of eomesodermin. J Immunol. 2010 Jul 01; 185(1):126-33. PMID: 20525896.
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    42. O'Brien RL, Born WK. gammadelta T cell subsets: a link between TCR and function? Semin Immunol. 2010 Aug; 22(4):193-8. PMID: 20451408.
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    43. Born WK, Yin Z, Hahn YS, Sun D, O'Brien RL. Analysis of gamma delta T cell functions in the mouse. J Immunol. 2010 Apr 15; 184(8):4055-61. PMID: 20368285.
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    44. Nian H, Shao H, Zhang G, Born WK, O'Brien RL, Kaplan HJ, Sun D. Regulatory effect of gammadelta T cells on IL-17+ uveitogenic T cells. Invest Ophthalmol Vis Sci. 2010 Sep; 51(9):4661-7. PMID: 20375337.
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    45. O'Brien R, Jin N, Huang Y, Aydintug MK, Roark C, Born W. Characteristics of IL-17-producing gammadelta T cells. Immunity. 2010 Jan 29; 32(1):1; author reply 2-4. PMID: 20152161.
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    46. Born WK, Huang Y, Jin N, Huang H, O'Brien RL. Balanced approach of gammadelta T cells to type 2 immunity. Immunol Cell Biol. 2010 Mar-Apr; 88(3):269-74. PMID: 20101253.
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    47. Zhang L, Jin N, Nakayama M, O'Brien RL, Eisenbarth GS, Born WK. Gamma delta T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23. J Autoimmun. 2010 Jun; 34(4):478-84. PMID: 20080388.
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    48. Born WK, Roark CL, Jin N, Wands JM, Kemal Aydintug M, Huang Y, Chain JL, Hahn YS, Simonian PL, Fontenot AP, O'Brien RL. Role of ?d T Cells in Lung Inflammation. Open Immunol J. 2009; 2:143-150. PMID: 26550059.
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    49. Simonian PL, Roark CL, Born WK, O'Brien RL, Fontenot AP. Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis. Transl Res. 2009 Nov; 154(5):222-7. PMID: 19840763.
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    50. Cui Y, Shao H, Lan C, Nian H, O'Brien RL, Born WK, Kaplan HJ, Sun D. Major role of gamma delta T cells in the generation of IL-17+ uveitogenic T cells. J Immunol. 2009 Jul 01; 183(1):560-7. PMID: 19542467.
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    51. Huang Y, Jin N, Roark CL, Aydintug MK, Wands JM, Huang H, O'Brien RL, Born WK. The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin. J Immunol. 2009 Jul 15; 183(2):849-55. PMID: 19542369.
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    52. Simonian PL, Roark CL, Wehrmann F, Lanham AM, Born WK, O'Brien RL, Fontenot AP. IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis. J Immunol. 2009 May 15; 182(10):6540-9. PMID: 19414809.
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    53. Born WK, O'Brien RL. Antigen-restricted gammadelta T-cell receptors? Arch Immunol Ther Exp (Warsz). 2009 Mar-Apr; 57(2):129-35. PMID: 19333730.
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    54. O'Brien RL, Roark CL, Born WK. IL-17-producing gammadelta T cells. Eur J Immunol. 2009 Mar; 39(3):662-6. PMID: 19283718.
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    55. French JD, Roark CL, Born WK, O'Brien RL. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009 Feb 15; 182(4):1892-900. PMID: 19201842.
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    56. Jin N, Roark CL, Miyahara N, Taube C, Aydintug MK, Wands JM, Huang Y, Hahn YS, Gelfand EW, O'Brien RL, Born WK. Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells. J Immunol. 2009 Feb 15; 182(4):2002-10. PMID: 19201853.
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    57. O'Brien RL, Taylor MA, Hartley J, Nuhsbaum T, Dugan S, Lahmers K, Aydintug MK, Wands JM, Roark CL, Born WK. Protective role of gammadelta T cells in spontaneous ocular inflammation. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3266-74. PMID: 19151391.
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    58. Wang S, Welte T, Fang H, Chang GJ, Born WK, O'Brien RL, Sun B, Fujii H, Kosuna K, Wang T. Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice. J Nutr. 2009 Mar; 139(3):598-602. PMID: 19141700.
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    59. Simonian PL, Roark CL, Wehrmann F, Lanham AK, Diaz del Valle F, Born WK, O'Brien RL, Fontenot AP. Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis. J Immunol. 2009 Jan 01; 182(1):657-65. PMID: 19109199.
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    60. Matsubara S, Takeda K, Jin N, Okamoto M, Matsuda H, Shiraishi Y, Park JW, McConville G, Joetham A, O'Brien RL, Dakhama A, Born WK, Gelfand EW. Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2009 Apr; 40(4):454-63. PMID: 18927346.
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    61. Cheng L, Cui Y, Shao H, Han G, Zhu L, Huang Y, O'Brien RL, Born WK, Kaplan HJ, Sun D. Mouse gammadelta T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells. J Neuroimmunol. 2008 Oct 15; 203(1):3-11. PMID: 18774183.
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    62. Hahn YS, Ji XY, Woo SI, Choi YK, Song MS, Shin KS, Jin N, O'Brien RL, Born WK. V?1+ ?d T cells reduce IL-10-producing CD4+CD25+ T cells in the lung of ovalbumin-sensitized and challenged mice. Immunol Lett. 2008 Dec 22; 121(2):87-92. PMID: 18840468.
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    63. Hamada S, Umemura M, Shiono T, Tanaka K, Yahagi A, Begum MD, Oshiro K, Okamoto Y, Watanabe H, Kawakami K, Roark C, Born WK, O'Brien R, Ikuta K, Ishikawa H, Nakae S, Iwakura Y, Ohta T, Matsuzaki G. IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver. J Immunol. 2008 Sep 01; 181(5):3456-63. PMID: 18714018.
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    64. Cook L, Miyahara N, Jin N, Wands JM, Taube C, Roark CL, Potter TA, Gelfand EW, O'Brien RL, Born WK. Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness. J Immunol. 2008 Jul 01; 181(1):309-19. PMID: 18566396.
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    65. Welte T, Lamb J, Anderson JF, Born WK, O'Brien RL, Wang T. Role of two distinct gammadelta T cell subsets during West Nile virus infection. FEMS Immunol Med Microbiol. 2008 Jul; 53(2):275-83. PMID: 18513355.
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    66. Aydintug MK, Roark CL, Chain JL, Born WK, O'Brien RL. Macrophages express multiple ligands for gammadelta TCRs. Mol Immunol. 2008 Jun; 45(11):3253-63. PMID: 18455236.
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    67. Roark CL, Simonian PL, Fontenot AP, Born WK, O'Brien RL. gammadelta T cells: an important source of IL-17. Curr Opin Immunol. 2008 Jun; 20(3):353-7. PMID: 18439808.
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    68. Roark CL, French JD, Taylor MA, Bendele AM, Born WK, O'Brien RL. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells. J Immunol. 2007 Oct 15; 179(8):5576-83. PMID: 17911645.
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    69. Jin N, Miyahara N, Roark CL, French JD, Aydintug MK, Matsuda JL, Gapin L, O'Brien RL, Gelfand EW, Born WK. Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells. J Immunol. 2007 Sep 01; 179(5):2961-8. PMID: 17709511.
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    70. Born WK, Jin N, Aydintug MK, Wands JM, French JD, Roark CL, O'Brien RL. gammadelta T lymphocytes-selectable cells within the innate system? J Clin Immunol. 2007 Mar; 27(2):133-44. PMID: 17333410.
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    71. O'Brien RL, Roark CL, Jin N, Aydintug MK, French JD, Chain JL, Wands JM, Johnston M, Born WK. gammadelta T-cell receptors: functional correlations. Immunol Rev. 2007 Feb; 215:77-88. PMID: 17291280.
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    72. Simonian PL, Roark CL, Diaz del Valle F, Palmer BE, Douglas IS, Ikuta K, Born WK, O'Brien RL, Fontenot AP. Regulatory role of gammadelta T cells in the recruitment of CD4+ and CD8+ T cells to lung and subsequent pulmonary fibrosis. J Immunol. 2006 Oct 01; 177(7):4436-43. PMID: 16982878.
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    73. Reardon CL, Hu LJ, Yin X, Born WK, Arden B, O'Brien R. A new mechanism for generating TCR diversity: A TCR Jalpha-like gene that inserts partial nucleotide sequences in a D-gene manner. Mol Immunol. 2007 Feb; 44(5):906-15. PMID: 16793139.
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    74. Born WK, Reardon CL, O'Brien RL. The function of gammadelta T cells in innate immunity. Curr Opin Immunol. 2006 Feb; 18(1):31-8. PMID: 16337364.
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    75. Wands JM, Roark CL, Aydintug MK, Jin N, Hahn YS, Cook L, Yin X, Dal Porto J, Lahn M, Hyde DM, Gelfand EW, Mason RJ, O'Brien RL, Born WK. Distribution and leukocyte contacts of gammadelta T cells in the lung. J Leukoc Biol. 2005 Nov; 78(5):1086-96. PMID: 16204632.
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    76. French JD, Roark CL, Born WK, O'brien RL. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14741-6. PMID: 16203967.
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    77. Reardon C, Born WK, O'Brien RL. A unique Vgamma5-T-cell population in the murine mammary gland. Mol Immunol. 2006 Mar; 43(7):1057-61. PMID: 16045990.
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    78. Jin N, Taube C, Sharp L, Hahn YS, Yin X, Wands JM, Roark CL, O'brien RL, Gelfand EW, Born WK. Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness. J Immunol. 2005 Mar 01; 174(5):2671-9. PMID: 15728474.
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    79. Huber SA, Born W, O'Brien R. Dual functions of murine gammadelta cells in inflammation and autoimmunity in coxsackievirus B3-induced myocarditis: role of Vgamma1+ and Vgamma4+ cells. Microbes Infect. 2005 Mar; 7(3):537-43. PMID: 15777711.
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    80. Chou YK, Culbertson N, Rich C, LaTocha D, Buenafe AC, Huan J, Link J, Wands JM, Born WK, Offner H, Bourdette DN, Burrows GG, Vandenbark AA. T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice. J Neurosci Res. 2004 Sep 01; 77(5):670-80. PMID: 15352213.
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    81. Aydintug MK, Roark CL, Yin X, Wands JM, Born WK, O'Brien RL. Detection of cell surface ligands for the gamma delta TCR using soluble TCRs. J Immunol. 2004 Apr 01; 172(7):4167-75. PMID: 15034029.
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    82. Lahn M, Kanehiro A, Hahn YS, Wands JM, Aydintug MK, O'Brien RL, Gelfand EW, Born WK. Aerosolized anti-T-cell-receptor antibodies are effective against airway inflammation and hyperreactivity. Int Arch Allergy Immunol. 2004 May; 134(1):49-55. PMID: 15051940.
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    83. Hahn YS, Taube C, Jin N, Sharp L, Wands JM, Aydintug MK, Lahn M, Huber SA, O'Brien RL, Gelfand EW, Born WK. Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. J Immunol. 2004 Mar 01; 172(5):2894-902. PMID: 14978091.
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    84. Cui ZH, Joetham A, Aydintug MK, Hahn YS, Born WK, Gelfand EW. Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells. Am J Respir Crit Care Med. 2003 Dec 01; 168(11):1324-32. PMID: 14644924.
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    85. Roark CL, Aydintug MK, Lewis J, Yin X, Lahn M, Hahn YS, Born WK, Tigelaar RE, O'Brien RL. Subset-specific, uniform activation among V gamma 6/V delta 1+ gamma delta T cells elicited by inflammation. J Leukoc Biol. 2004 Jan; 75(1):68-75. PMID: 14525969.
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    86. Hahn YS, Taube C, Jin N, Takeda K, Park JW, Wands JM, Aydintug MK, Roark CL, Lahn M, O'Brien RL, Gelfand EW, Born WK. V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice. J Immunol. 2003 Sep 15; 171(6):3170-8. PMID: 12960345.
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    87. Rha YH, Taube C, Haczku A, Joetham A, Takeda K, Duez C, Siegel M, Aydintug MK, Born WK, Dakhama A, Gelfand EW. Effect of microbial heat shock proteins on airway inflammation and hyperresponsiveness. J Immunol. 2002 Nov 01; 169(9):5300-7. PMID: 12391250.
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    88. Kanehiro A, Lahn M, Mäkelä MJ, Dakhama A, Joetham A, Rha YH, Born W, Gelfand EW. Requirement for the p75 TNF-alpha receptor 2 in the regulation of airway hyperresponsiveness by gamma delta T cells. J Immunol. 2002 Oct 15; 169(8):4190-7. PMID: 12370348.
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    89. Lahn M, Kanehiro A, Takeda K, Terry J, Hahn YS, Aydintug MK, Konowal A, Ikuta K, O'Brien RL, Gelfand EW, Born WK. MHC class I-dependent Vgamma4+ pulmonary T cells regulate alpha beta T cell-independent airway responsiveness. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8850-5. PMID: 12070351.
      View in: PubMed
    90. Born WK, O'Brien RL. The healing touch of epidermal T cells. Nat Med. 2002 Jun; 8(6):560-1. PMID: 12042801.
      View in: PubMed
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