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Rosemary Rochford

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology

    Collapse Research 
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    R01AG009822     (ROCHFORD, ROSEMARY)Jan 15, 1992 - Jul 31, 2002
    NIH/NIA
    CYTOKINE GENE EXPRESSION BY CD4+ CELLS IN AGING MICE
    Role: Principal Investigator

    R01CA073556     (ROCHFORD, ROSEMARY)Mar 1, 1997 - Dec 31, 2001
    NIH/NCI
    PATHOGENESIS OF EBV ASSOCIATED AIDS LYMPHOMAS
    Role: Principal Investigator

    R01CA102667     (ROCHFORD, ROSEMARY)Jul 1, 2003 - Jul 31, 2015
    NIH/NCI
    Effects of Malaria on EBV Persistence in Children
    Role: Principal Investigator

    R21CA119918     (ROCHFORD, ROSEMARY)May 1, 2007 - Apr 30, 2009
    NIH/NCI
    Antiangiogenic Therapy for AIDS-Associated Lymphomas
    Role: Principal Investigator

    R03TW007821     (ROCHFORD, ROSEMARY)Apr 1, 2008 - Mar 31, 2012
    NIH/FIC
    Micronutrient Malnutrition and EBV Persistence in Children
    Role: Principal Investigator

    R21AI122670     (PELANDA, ROBERTA)Jan 1, 2016 - Dec 31, 2017
    NIH/NIAID
    Developing a new model for EBV-mediated T cell diseases
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Coleman CB, Daud II, Ogolla SO, Ritchie JA, Smith NA, Sumba PO, Dent AE, Rochford R. Epstein-Barr Virus Type 2 Infects T Cells in Healthy Kenyan Children. J Infect Dis. 2017 Sep 15; 216(6):670-677. PMID: 28934430.
      View in: PubMed
    2. Haverkos BM, Coleman C, Gru AA, Pan Z, Brammer J, Rochford R, Mishra A, Oakes CC, Baiocchi RA, Freud AG, Porcu P. Emerging insights on the pathogenesis and treatment of extranodal NK/T cell lymphomas (ENKTL). Discov Med. 2017 Mar; 23(126):189-199. PMID: 28472613.
      View in: PubMed
    3. Heydari N, Larsen DA, Neira M, Beltrán Ayala E, Fernandez P, Adrian J, Rochford R, Stewart-Ibarra AM. Household Dengue Prevention Interventions, Expenditures, and Barriers to Aedes aegypti Control in Machala, Ecuador. Int J Environ Res Public Health. 2017 Feb 16; 14(2). PMID: 28212349.
      View in: PubMed
    4. Toko EN, Sumba OP, Daud II, Ogolla S, Majiwa M, Krisher JT, Ouma C, Dent AE, Rochford R, Mehta S. Maternal Vitamin D Status and Adverse Birth Outcomes in Children from Rural Western Kenya. Nutrients. 2016 Dec 07; 8(12). PMID: 27941597.
      View in: PubMed
    5. Haverkos BM, Pan Z, Gru AA, Freud AG, Rabinovitch R, Xu-Welliver M, Otto B, Barrionuevo C, Baiocchi RA, Rochford R, Porcu P. Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases. Curr Hematol Malig Rep. 2016 Dec; 11(6):514-527. PMID: 27778143.
      View in: PubMed
    6. Krisher LK, Krisher J, Ambuludi M, Arichabala A, Beltrán-Ayala E, Navarrete P, Ordoñez T, Polhemus ME, Quintana F, Rochford R, Silva M, Bazo J, Stewart-Ibarra AM. Successful malaria elimination in the Ecuador-Peru border region: epidemiology and lessons learned. Malar J. 2016 Nov 28; 15(1):573. PMID: 27894320.
      View in: PubMed
    7. Reynaldi A, Schlub TE, Piriou E, Ogolla S, Sumba OP, Moormann AM, Rochford R, Davenport MP. Modeling of EBV Infection and Antibody Responses in Kenyan Infants With Different Levels of Malaria Exposure Shows Maternal Antibody Decay is a Major Determinant of Early EBV Infection. J Infect Dis. 2016 Nov 01; 214(9):1390-1398. PMID: 27571902.
      View in: PubMed
    8. Rochford R, Korir A, Newton R. Viral-associated malignancies in Africa: are viruses 'infectious traces' or 'dominant drivers'? Curr Opin Virol. 2016 Oct; 20:28-33. PMID: 27551983.
      View in: PubMed
    9. Gru AA, Haverkos BH, Freud AG, Hastings J, Nowacki NB, Barrionuevo C, Vigil CE, Rochford R, Natkunam Y, Baiocchi RA, Porcu P. The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment. Curr Hematol Malig Rep. 2015 Dec; 10(4):456-67. PMID: 26449716.
      View in: PubMed
    10. Reynaldi A, Schlub TE, Chelimo K, Sumba PO, Piriou E, Ogolla S, Moormann AM, Rochford R, Davenport MP. Impact of Plasmodium falciparum Coinfection on Longitudinal Epstein-Barr Virus Kinetics in Kenyan Children. J Infect Dis. 2016 Mar 15; 213(6):985-91. PMID: 26531246; PMCID: PMC4760420 [Available on 03/15/17].
    11. Ogolla S, Daud II, Asito AS, Sumba OP, Ouma C, Vulule J, Middeldorp JM, Dent AE, Mehta S, Rochford R. Reduced Transplacental Transfer of a Subset of Epstein-Barr Virus-Specific Antibodies to Neonates of Mothers Infected with Plasmodium falciparum Malaria during Pregnancy. Clin Vaccine Immunol. 2015 Nov; 22(11):1197-205. PMID: 26376931; PMCID: PMC4622112.
    12. Daud II, Coleman CB, Smith NA, Ogolla S, Simbiri K, Bukusi EA, Ng'ang'a ZW, Sumba PO, Vulule J, Ploutz-Snyder R, Dent AE, Rochford R. Breast Milk as a Potential Source of Epstein-Barr Virus Transmission Among Infants Living in a Malaria-Endemic Region of Kenya. J Infect Dis. 2015 Dec 01; 212(11):1735-42. PMID: 25985902; PMCID: PMC4633760 [Available on 12/01/16].
    13. Simbiri KO, Smith NA, Otieno R, Wohlford EE, Daud II, Odada SP, Middleton F, Rochford R. Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population. PLoS One. 2015; 10(5):e0125420. PMID: 25933165; PMCID: PMC4416826.
    14. Daud II, Ogolla S, Amolo AS, Namuyenga E, Simbiri K, Bukusi EA, Ng'ang'a ZW, Ploutz-Snyder R, Sumba PO, Dent A, Rochford R. Plasmodium falciparum infection is associated with Epstein-Barr virus reactivation in pregnant women living in malaria holoendemic area of Western Kenya. Matern Child Health J. 2015 Mar; 19(3):606-14. PMID: 24951129; PMCID: PMC4272914.
    15. Rochford R, Moormann AM. Burkitt's Lymphoma. Curr Top Microbiol Immunol. 2015; 390(Pt 1):267-85. PMID: 26424650.
      View in: PubMed
    16. Coleman CB, Wohlford EM, Smith NA, King CA, Ritchie JA, Baresel PC, Kimura H, Rochford R. Epstein-Barr virus type 2 latently infects T cells, inducing an atypical activation characterized by expression of lymphotactic cytokines. J Virol. 2015 Feb; 89(4):2301-12. PMID: 25505080; PMCID: PMC4338898.
    17. Wilmore JR, Asito AS, Wei C, Piriou E, Sumba PO, Sanz I, Rochford R. AID expression in peripheral blood of children living in a malaria holoendemic region is associated with changes in B cell subsets and Epstein-Barr virus. Int J Cancer. 2015 Mar 15; 136(6):1371-80. PMID: 25099163; PMCID: PMC4697832.
    18. Korir A, Mauti N, Moats P, Gurka MJ, Mutuma G, Metheny C, Mwamba PM, Oyiro PO, Fisher M, Ayers LW, Rochford R, Mwanda WO, Remick SC. Developing clinical strength-of-evidence approach to define HIV-associated malignancies for cancer registration in Kenya. PLoS One. 2014; 9(1):e85881. PMID: 24465764; PMCID: PMC3900436.
    19. Wohlford EM, Asito AS, Chelimo K, Sumba PO, Baresel PC, Oot RA, Moormann AM, Rochford R. Identification of a novel variant of LMP-1 of EBV in patients with endemic Burkitt lymphoma in western Kenya. Infect Agent Cancer. 2013 Sep 09; 8(1):34. PMID: 24016332; PMCID: PMC3847075.
    20. Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S. Burkitt's lymphoma. Lancet. 2012 Mar 31; 379(9822):1234-44. PMID: 22333947.
      View in: PubMed
    21. Piriou E, Asito AS, Sumba PO, Fiore N, Middeldorp JM, Moormann AM, Ploutz-Snyder R, Rochford R. Early age at time of primary Epstein-Barr virus infection results in poorly controlled viral infection in infants from Western Kenya: clues to the etiology of endemic Burkitt lymphoma. J Infect Dis. 2012 Mar 15; 205(6):906-13. PMID: 22301635; PMCID: PMC3282570.
    22. Asito AS, Piriou E, Jura WG, Ouma C, Odada PS, Ogola S, Fiore N, Rochford R. Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya. Malar J. 2011 Dec 13; 10:362. PMID: 22166136; PMCID: PMC3315680.
    23. Sumba PO, Kabiru EW, Namuyenga E, Fiore N, Otieno RO, Moormann AM, Orago AS, Rosenbaum PF, Rochford R. Microgeographic variations in Burkitt's lymphoma incidence correlate with differences in malnutrition, malaria and Epstein-Barr virus. Br J Cancer. 2010 Nov 23; 103(11):1736-41. PMID: 21102592; PMCID: PMC2994219.
    24. Spring MD, Chelimo K, Tisch DJ, Sumba PO, Rochford R, Long CA, Kazura JW, Moormann AM. Allele specificity of gamma interferon responses to the carboxyl-terminal region of Plasmodium falciparum merozoite surface protein 1 by Kenyan adults with naturally acquired immunity to malaria. Infect Immun. 2010 Oct; 78(10):4431-41. PMID: 20696832; PMCID: PMC2950343.
    25. Piriou E, Kimmel R, Chelimo K, Middeldorp JM, Odada PS, Ploutz-Snyder R, Moormann AM, Rochford R. Serological evidence for long-term Epstein-Barr virus reactivation in children living in a holoendemic malaria region of Kenya. J Med Virol. 2009 Jun; 81(6):1088-93. PMID: 19382256; PMCID: PMC3134942.
    26. Moormann AM, Heller KN, Chelimo K, Embury P, Ploutz-Snyder R, Otieno JA, Oduor M, Münz C, Rochford R. Children with endemic Burkitt lymphoma are deficient in EBNA1-specific IFN-gamma T cell responses. Int J Cancer. 2009 Apr 01; 124(7):1721-6. PMID: 19089927; PMCID: PMC2708320.
    27. Asito AS, Moormann AM, Kiprotich C, Ng'ang'a ZW, Ploutz-Snyder R, Rochford R. Alterations on peripheral B cell subsets following an acute uncomplicated clinical malaria infection in children. Malar J. 2008 Nov 18; 7:238. PMID: 19019204; PMCID: PMC2626599.
    28. Rainey JJ, Rochford R, Sumba PO, Kowuor D, Wilson ML, Moormann AM. Family environment is associated with endemic Burkitt lymphoma: a population-based case-control study. Am J Trop Med Hyg. 2008 Feb; 78(2):338-43. PMID: 18256442.
      View in: PubMed
    29. Rainey JJ, Mwanda WO, Wairiumu P, Moormann AM, Wilson ML, Rochford R. Spatial distribution of Burkitt's lymphoma in Kenya and association with malaria risk. Trop Med Int Health. 2007 Aug; 12(8):936-43. PMID: 17697088.
      View in: PubMed
    30. Moormann AM, Chelimo K, Sumba PO, Tisch DJ, Rochford R, Kazura JW. Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children. J Infect Dis. 2007 Mar 15; 195(6):799-808. PMID: 17299709.
      View in: PubMed
    31. Rainey JJ, Omenah D, Sumba PO, Moormann AM, Rochford R, Wilson ML. Spatial clustering of endemic Burkitt's lymphoma in high-risk regions of Kenya. Int J Cancer. 2007 Jan 01; 120(1):121-7. PMID: 17019706.
      View in: PubMed
    32. Banerjee P, Rochford R, Antel J, Canute G, Wrzesinski S, Sieburg M, Feuer G. Proinflammatory cytokine gene induction by human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 Tax in primary human glial cells. J Virol. 2007 Feb; 81(4):1690-700. PMID: 17121800; PMCID: PMC1797548.
    33. Moormann AM, Chelimo K, Sumba OP, Lutzke ML, Ploutz-Snyder R, Newton D, Kazura J, Rochford R. Exposure to holoendemic malaria results in elevated Epstein-Barr virus loads in children. J Infect Dis. 2005 Apr 15; 191(8):1233-8. PMID: 15776368.
      View in: PubMed
    34. Rochford R, Cannon MJ, Moormann AM. Endemic Burkitt's lymphoma: a polymicrobial disease? Nat Rev Microbiol. 2005 02; 3(2):182-7. PMID: 15685227.
      View in: PubMed
    35. Wu W, Rochford R, Toomey L, Harrington W, Feuer G. Inhibition of HHV-8/KSHV infected primary effusion lymphomas in NOD/SCID mice by azidothymidine and interferon-alpha. Leuk Res. 2005 May; 29(5):545-55. PMID: 15755507.
      View in: PubMed
    36. Woodford NL, Call DR, Remick DG, Rochford R. Model of angiogenesis in mice with severe combined immunodeficiency (SCID) and xenoengrafted with Epstein-Barr virus-transformed B cells. Comp Med. 2004 Apr; 54(2):209-15. PMID: 15134368.
      View in: PubMed
    37. Khanolkar A, Fu Z, Underwood LJ, Bondurant KL, Rochford R, Cannon MJ. CD4+ T cell-induced differentiation of EBV-transformed lymphoblastoid cells is associated with diminished recognition by EBV-specific CD8+ cytotoxic T cells. J Immunol. 2003 Mar 15; 170(6):3187-94. PMID: 12626577.
      View in: PubMed
    38. Kleer CG, Tseng MD, Gutsch DE, Rochford RA, Wu Z, Joynt LK, Helvie MA, Chang T, Van Golen KL, Merajver SD. Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts. Mod Pathol. 2002 Jul; 15(7):759-64. PMID: 12118114.
      View in: PubMed
    39. Tkachuk AN, Moormann AM, Poore JA, Rochford RA, Chensue SW, Mwapasa V, Meshnick SR. Malaria enhances expression of CC chemokine receptor 5 on placental macrophages. J Infect Dis. 2001 Mar 15; 183(6):967-72. PMID: 11237815.
      View in: PubMed
    40. Moormann AM, Sullivan AD, Rochford RA, Chensue SW, Bock PJ, Nyirenda T, Meshnick SR. Malaria and pregnancy: placental cytokine expression and its relationship to intrauterine growth retardation. J Infect Dis. 1999 Dec; 180(6):1987-93. PMID: 10558956.
      View in: PubMed
    41. Nazaruk RA, Rochford R, Hobbs MV, Cannon MJ. Functional diversity of the CD8(+) T-cell response to Epstein-Barr virus (EBV): implications for the pathogenesis of EBV-associated lymphoproliferative disorders. Blood. 1998 May 15; 91(10):3875-83. PMID: 9573025.
      View in: PubMed
    42. Rochford R, Miller CL, Cannon MJ, Izumi KM, Kieff E, Longnecker R. In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2). Arch Virol. 1997; 142(4):707-20. PMID: 9170499.
      View in: PubMed
    43. Rochford R, Hobbs MV, Garnier JL, Cooper NR, Cannon MJ. Plasmacytoid differentiation of Epstein-Barr virus-transformed B cells in vivo is associated with reduced expression of viral latent genes. Proc Natl Acad Sci U S A. 1993 Jan 01; 90(1):352-6. PMID: 8380497; PMCID: PMC45658.
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