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Joseph Damian Spahn

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Spahn JD, Malka J, Szefler SJ. Current application of exhaled nitric oxide in clinical practice. J Allergy Clin Immunol. 2016 Nov; 138(5):1296-1298. PMID: 27664377.
      View in: PubMed
    2. Federico MJ, Hoch HE, Anderson WC, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug; 63(1):103-26. PMID: 27426897.
      View in: PubMed
    3. Malka J, Spahn JD. When Cough Wheeze and Shortness of Breath Don't Equal Asthma. J Allergy Clin Immunol Pract. 2016 Jan-Feb; 4(1):179-81; quiz 182-3. PMID: 26772931.
      View in: PubMed
    4. Malka J, Covar R, Faino A, Fish J, Pickering P, Ramamoorthy P, Gleason M, Spahn JD. The Effect of Viral Infection on Exhaled Nitric Oxide in Children with Acute Asthma Exacerbations. J Allergy Clin Immunol Pract. 2015 Nov-Dec; 3(6):913-9. PMID: 26216254.
      View in: PubMed
    5. Santos CB, Davidson J, Covar RA, Spahn JD. The chitinase-like protein YKL-40 is not a useful biomarker for severe persistent asthma in children. Ann Allergy Asthma Immunol. 2014 Sep; 113(3):263-6. PMID: 24954373.
      View in: PubMed
    6. Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug; 134(2):483-5. PMID: 24835502; PMCID: PMC4119870.
    7. Reddy MB, Doshi J, Covar R, Spahn JD. The changing face of severe childhood asthma: a comparison of two cohorts of children evaluated at National Jewish Health over the past 20 years. Allergy Asthma Proc. 2014 Mar-Apr; 35(2):119-25. PMID: 24717788.
      View in: PubMed
    8. Mahr TA, Malka J, Spahn JD. Inflammometry in pediatric asthma: a review of fractional exhaled nitric oxide in clinical practice. Allergy Asthma Proc. 2013 May-Jun; 34(3):210-9. PMID: 23462278.
      View in: PubMed
    9. Spahn JD. Asthma biomarkers in sputum. Immunol Allergy Clin North Am. 2012 Aug; 32(3):387-99. PMID: 22877617.
      View in: PubMed
    10. Lemanske RF, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Covar RA, Guilbert TW, Larsen G, Morgan WJ, Moss MH, Spahn JD, Taussig LM. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med. 2010 Mar 18; 362(11):975-85. PMID: 20197425; PMCID: PMC2989902.
    11. Covar RA, Strunk R, Zeiger RS, Wilson LA, Liu AH, Weiss S, Tonascia J, Spahn JD, Szefler SJ. Predictors of remitting, periodic, and persistent childhood asthma. J Allergy Clin Immunol. 2010 Feb; 125(2):359-366.e3. PMID: 20159245; PMCID: PMC2844768.
    12. Spahn J, Sheth K, Yeh WS, Stempel DA, Stanford RH. Dispensing of fluticasone propionate/salmeterol combination in the summer and asthma-related outcomes in the fall. J Allergy Clin Immunol. 2009 Dec; 124(6):1197-203. PMID: 19910037.
      View in: PubMed
    13. Holt EW, Cook EF, Covar RA, Spahn J, Fuhlbrigge AL. Identifying the components of asthma health status in children with mild to moderate asthma. J Allergy Clin Immunol. 2008 May; 121(5):1175-80. PMID: 18466785; PMCID: PMC3036169.
    14. Spahn JD, Covar R. Clinical assessment of asthma progression in children and adults. J Allergy Clin Immunol. 2008 Mar; 121(3):548-57; quiz 558-9. PMID: 18328886.
      View in: PubMed
    15. Spahn JD. Asthma biomarkers in sputum. Immunol Allergy Clin North Am. 2007 Nov; 27(4):607-22; vi. PMID: 17996579.
      View in: PubMed
    16. Spahn JD, Szefler SJ. Steroid therapy for asthma in children. Curr Opin Pediatr. 2007 Jun; 19(3):300-5. PMID: 17505190.
      View in: PubMed
    17. Sorkness CA, Lemanske RF, Mauger DT, Boehmer SJ, Chinchilli VM, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bloomberg GR, Covar RA, Guilbert TW, Heldt G, Larsen G, Mellon MH, Morgan WJ, Moss MH, Spahn JD, Taussig LM. Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial. J Allergy Clin Immunol. 2007 Jan; 119(1):64-72. PMID: 17140647.
      View in: PubMed
    18. Chipps BE, Spahn JD. What are the determinates of asthma control? J Asthma. 2006 Oct; 43(8):567-72. PMID: 17050219.
      View in: PubMed
    19. Fuhlbrigge AL, Guilbert T, Spahn J, Peden D, Davis K. The influence of variation in type and pattern of symptoms on assessment in pediatric asthma. Pediatrics. 2006 Aug; 118(2):619-25. PMID: 16882815.
      View in: PubMed
    20. Stempel DA, Spahn JD, Stanford RH, Rosenzweig JR, McLaughlin TP. The economic impact of children dispensed asthma medications without an asthma diagnosis. J Pediatr. 2006 Jun; 148(6):819-23. PMID: 16769395.
      View in: PubMed
    21. Spahn JD, Liu AH. The inner-city asthma epidemic reaches far and wide. Ann Allergy Asthma Immunol. 2006 Jun; 96(6):759-61. PMID: 16802759.
      View in: PubMed
    22. Chipps BE, Spahn JD, Sorkness CA, Baitinger L, Sutton LB, Emmett AH, Dorinsky PM. Variability in asthma severity in pediatric subjects with asthma previously receiving short-acting beta2-agonists. J Pediatr. 2006 Apr; 148(4):517-21. PMID: 16647416.
      View in: PubMed
    23. Spahn JD, Covar RA, Jain N, Gleason M, Shimamoto R, Szefler SJ, Gelfand EW. Effect of montelukast on peripheral airflow obstruction in children with asthma. Ann Allergy Asthma Immunol. 2006 Apr; 96(4):541-9. PMID: 16680924.
      View in: PubMed
    24. Zeiger RS, Szefler SJ, Phillips BR, Schatz M, Martinez FD, Chinchilli VM, Lemanske RF, Strunk RC, Larsen G, Spahn JD, Bacharier LB, Bloomberg GR, Guilbert TW, Heldt G, Morgan WJ, Moss MH, Sorkness CA, Taussig LM. Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma. J Allergy Clin Immunol. 2006 Jan; 117(1):45-52. PMID: 16387583.
      View in: PubMed
    25. Spahn JD, Chipps BE. Office-based objective measures in childhood asthma. J Pediatr. 2006 Jan; 148(1):11-5. PMID: 16423591.
      View in: PubMed
    26. Jain N, Covar RA, Gleason MC, Newell JD, Gelfand EW, Spahn JD. Quantitative computed tomography detects peripheral airway disease in asthmatic children. Pediatr Pulmonol. 2005 Sep; 40(3):211-8. PMID: 16015663.
      View in: PubMed
    27. Paull K, Covar R, Jain N, Gelfand EW, Spahn JD. Do NHLBI lung function criteria apply to children? A cross-sectional evaluation of childhood asthma at National Jewish Medical and Research Center, 1999-2002. Pediatr Pulmonol. 2005 Apr; 39(4):311-7. PMID: 15678505.
      View in: PubMed
    28. Federico MJ, Covar RA, Brown EE, Leung DY, Spahn JD. Racial differences in T-lymphocyte response to glucocorticoids. Chest. 2005 Feb; 127(2):571-8. PMID: 15705998.
      View in: PubMed
    29. Szefler SJ, Phillips BR, Martinez FD, Chinchilli VM, Lemanske RF, Strunk RC, Zeiger RS, Larsen G, Spahn JD, Bacharier LB, Bloomberg GR, Guilbert TW, Heldt G, Morgan WJ, Moss MH, Sorkness CA, Taussig LM. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J Allergy Clin Immunol. 2005 Feb; 115(2):233-42. PMID: 15696076.
      View in: PubMed
    30. Covar RA, Spahn JD, Martin RJ, Silkoff PE, Sundstrom DA, Murphy J, Szefler SJ. Safety and application of induced sputum analysis in childhood asthma. J Allergy Clin Immunol. 2004 Sep; 114(3):575-82. PMID: 15356559.
      View in: PubMed
    31. Guilbert TW, Morgan WJ, Krawiec M, Lemanske RF, Sorkness C, Szefler SJ, Larsen G, Spahn JD, Zeiger RS, Heldt G, Strunk RC, Bacharier LB, Bloomberg GR, Chinchilli VM, Boehmer SJ, Mauger EA, Mauger DT, Taussig LM, Martinez FD. The Prevention of Early Asthma in Kids study: design, rationale and methods for the Childhood Asthma Research and Education network. Control Clin Trials. 2004 Jun; 25(3):286-310. PMID: 15157730.
      View in: PubMed
    32. Covar RA, Spahn JD, Murphy JR, Szefler SJ. Progression of asthma measured by lung function in the childhood asthma management program. Am J Respir Crit Care Med. 2004 Aug 01; 170(3):234-41. PMID: 15028558.
      View in: PubMed
    33. Spahn JD, Cherniack R, Paull K, Gelfand EW. Is forced expiratory volume in one second the best measure of severity in childhood asthma? Am J Respir Crit Care Med. 2004 Apr 01; 169(7):784-6. PMID: 14754761.
      View in: PubMed
    34. Spahn J. Clinical trial efficacy: what does it really tell you? J Allergy Clin Immunol. 2003 Nov; 112(5 Suppl):S102-6. PMID: 14586394.
      View in: PubMed
    35. Szefler SJ, Whelan G, Gleason M, Spahn JD. The need for pediatric studies of allergy and asthma medications. Curr Allergy Asthma Rep. 2003 Nov; 3(6):478-83. PMID: 14531968.
      View in: PubMed
    36. Jenkins HA, Cherniack R, Szefler SJ, Covar R, Gelfand EW, Spahn JD. A comparison of the clinical characteristics of children and adults with severe asthma. Chest. 2003 Oct; 124(4):1318-24. PMID: 14555561.
      View in: PubMed
    37. Jenkins HA, Cool C, Szefler SJ, Covar R, Brugman S, Gelfand EW, Spahn JD. Histopathology of severe childhood asthma: a case series. Chest. 2003 Jul; 124(1):32-41. PMID: 12853499.
      View in: PubMed
    38. Covar RA, Spahn JD. Treating the wheezing infant. Pediatr Clin North Am. 2003 Jun; 50(3):631-54. PMID: 12892044.
      View in: PubMed
    39. Spahn JD, Covar RA. Weighing the risks of treatment versus nontreatment in pediatric asthma. Pediatr Clin North Am. 2003 Jun; 50(3):677-95. PMID: 12877241.
      View in: PubMed
    40. Covar RA, Szefler SJ, Martin RJ, Sundstrom DA, Silkoff PE, Murphy J, Young DA, Spahn JD. Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma. J Pediatr. 2003 May; 142(5):469-75. PMID: 12756375.
      View in: PubMed
    41. Spahn JD, Szefler SJ. Inhaled steroids: are they all created equal? Semin Respir Crit Care Med. 2002 Aug; 23(4):377-86. PMID: 16088631.
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    42. Leung DY, Spahn JD, Szefler SJ. Steroid-unresponsive asthma. Semin Respir Crit Care Med. 2002 Aug; 23(4):387-98. PMID: 16088632.
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    43. Spahn J, Covar R, Stempel DA. Asthma: addressing consistency in results from basic science, clinical trials, and observational experience. J Allergy Clin Immunol. 2002 May; 109(5 Suppl):S490-502. PMID: 11994721.
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    44. Spahn JD, Szefler SJ. Childhood asthma: new insights into management. J Allergy Clin Immunol. 2002 Jan; 109(1):3-13. PMID: 11799358.
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    45. Spahn JD, Fost DA, Covar R, Martin RJ, Brown EE, Szefler SJ, Leung DY. Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. Ann Allergy Asthma Immunol. 2001 Dec; 87(6):501-5. PMID: 11770698.
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    46. Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF, Sorkness CA, Kraft M, Fish JE, Peters SP, Craig T, Drazen JM, Ford JG, Israel E, Martin RJ, Mauger EA, Nachman SA, Spahn JD, Szefler SJ. Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2583-93. PMID: 11368732.
      View in: PubMed
    47. Lemanske RF, Sorkness CA, Mauger EA, Lazarus SC, Boushey HA, Fahy JV, Drazen JM, Chinchilli VM, Craig T, Fish JE, Ford JG, Israel E, Kraft M, Martin RJ, Nachman SA, Peters SP, Spahn JD, Szefler SJ. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2594-603. PMID: 11368733.
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    48. Covar RA, Leung DY, McCormick D, Steelman J, Zeitler P, Spahn JD. Risk factors associated with glucocorticoid-induced adverse effects in children with severe asthma. J Allergy Clin Immunol. 2000 Oct; 106(4):651-9. PMID: 11031335.
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    49. Wamboldt FS, Spahn JD, Klinnert MD, Wamboldt MZ, Gavin LA, Szefler SJ, Leung DY. Clinical outcomes of steroid-insensitive asthma. Ann Allergy Asthma Immunol. 1999 Jul; 83(1):55-60. PMID: 10437817.
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    50. Fost DA, Leung DY, Martin RJ, Brown EE, Szefler SJ, Spahn JD. Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy. J Allergy Clin Immunol. 1999 Jun; 103(6):1031-5. PMID: 10359882.
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    51. Spahn JD, Leung DY, Chan MT, Szefler SJ, Gelfand EW. Mechanisms of glucocorticoid reduction in asthmatic subjects treated with intravenous immunoglobulin. J Allergy Clin Immunol. 1999 Mar; 103(3 Pt 1):421-6. PMID: 10069875.
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    52. Leung DY, Spahn JD, Szefler SJ. Immunologic basis and management of steroid-resistant asthma. Allergy Asthma Proc. 1999 Jan-Feb; 20(1):9-14. PMID: 10076704.
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    53. Nimmagadda SR, Spahn JD, Nelson HS, Jenkins J, Szefler SJ, Leung DY. Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma. Ann Allergy Asthma Immunol. 1998 Jul; 81(1):35-40. PMID: 9690571.
      View in: PubMed
    54. Chan MT, Leung DY, Szefler SJ, Spahn JD. Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma. J Allergy Clin Immunol. 1998 May; 101(5):594-601. PMID: 9600494.
      View in: PubMed
    55. Spahn JD. Is fluticasone propionate superior to the other available inhaled steroids? J Asthma. 1998; 35(4):307-11. PMID: 9669825.
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    56. Spahn JD, Leung DY, Szefler SJ. New insights into the pathogenesis and management of steroid-resistant asthma. J Asthma. 1997; 34(3):177-94. PMID: 9168845.
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    57. Nimmagadda SR, Szefler SJ, Spahn JD, Surs W, Leung DY. Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med. 1997 Jan; 155(1):87-93. PMID: 9001294.
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    58. Spahn JD, Landwehr LP, Nimmagadda S, Surs W, Leung DY, Szefler SJ. Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma. J Allergy Clin Immunol. 1996 Dec; 98(6 Pt 1):1073-9. PMID: 8977508.
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    59. Spahn JD, Leung DY. The role of glucocorticoids in the management of asthma. Allergy Asthma Proc. 1996 Nov-Dec; 17(6):341-50. PMID: 8993728.
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    60. Nimmagadda SR, Spahn JD, Leung DY, Szefler SJ. Steroid-resistant asthma: evaluation and management. Ann Allergy Asthma Immunol. 1996 Nov; 77(5):345-55; quiz 355-6. PMID: 8933772.
      View in: PubMed
    61. Spahn JD, Szefler SJ, Surs W, Doherty DE, Nimmagadda SR, Leung DY. A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity. J Immunol. 1996 Sep 15; 157(6):2654-9. PMID: 8805670.
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    62. Leung DY, Spahn JD, Nimmagadda SR, Szefler SJ. Induction of corticosteroid resistance in vitro. Am J Respir Crit Care Med. 1996 Aug; 154(2 Pt 2):S34-7; discussion S37-8. PMID: 8756785.
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    63. Spahn JD, Kamada AK. Special considerations in the use of glucocorticoids in children. Pediatr Rev. 1995 Jul; 16(7):266-72. PMID: 7624279.
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    64. Spahn JD, Leung DY, Surs W, Harbeck RJ, Nimmagadda S, Szefler SJ. Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation. Am J Respir Crit Care Med. 1995 Jun; 151(6):1709-14. PMID: 7767511.
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    65. Kamada AK, Spahn JD, Blake KV. Salmeterol: its place in asthma management. Ann Pharmacother. 1994 Sep; 28(9):1100-2. PMID: 7803888.
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    66. Kamada AK, Spahn JD, Surs W, Brown E, Leung DY, Szefler SJ. Coexistence of glucocorticoid receptor and pharmacokinetic abnormalities: factors that contribute to a poor response to treatment with glucocorticoids in children with asthma. J Pediatr. 1994 Jun; 124(6):984-6. PMID: 8201491.
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    67. Lake FR, Dempsey EC, Spahn JD, Riches DW. Involvement of protein kinase C in macrophage activation by poly(I.C). Am J Physiol. 1994 Jan; 266(1 Pt 1):C134-42. PMID: 8304411.
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    68. Caplin I, Haynes JT, Spahn J. Are nasal polyps an allergic phenomenon? Ann Allergy. 1971 Dec; 29(12):631-4. PMID: 5126837.
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