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Yasmeen Maisha Nkrumah-Elie

TitlePost-Doctoral Fellow
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Biography 
    Collapse awards and honors
    20162nd Place for Clinical Research Oral Presentation, University of Colorado, Denver Postdoctoral Association
    20161st Place Poster, New Strategies and Challenges in Lung Proteomics and Metabolomics Workshop
    2015University of Colorado, Denver Representative, American Institute for Medical & Biological Engineers Public Policy Institute for Rising Leaders
    2015Domestic ToxScholar, Society of Toxicology, Diversity Initiatives
    2015Early Career Travel Award, San Francisco, CA, Metabolomics Society
    2015Travel Award, Postdoctoral Association, University of Colorado, Denver
    2014Travel Award, American Society for Nutrition/ Maximizing Access to Research Careers
    2014Young Minority Investigator Oral Competition Finalist, American Society for Nutrition
    2013Young Investigator Award, Diet and Optimal Health Conference, Corvallis, Oregon
    2013Travel Award for Annual Experimental Biology Meeting, San Diego, CA, Federation of American Societies for Experimental Biology
    2012 - 2014Ruth L. Kirschstein National Research Service Award Postdoctoral Trainee, National Institutes of Health & Oregon State University
    2011Inductee, Rho Chi Pharmaceutical Sciences Honor Society
    2009Charles A. Walker Award for Excellence in Graduate Research and Community Service, Florida A&M University (FAMU) College of Pharmacy and Pharmaceutical Sciences
    20081st Place Award in Biomolecular Sciences, FAMU Annual Student Research Forum 2008
    2006Minority Scholar, American Association for Cancer Research
    2005Russell V. Ewald Award for Academic Excellence, Florida Education Fund
    2003 - 2011McKnight Doctoral Fellow, Florida Education Fund
    1999Inductee, Tau Beta Pi Engineering Honor Society
    1999Inductee, Golden Key International Honor Society
    1997 - 2002Presidential Scholarship, FAMU
    1997 - 2000Engineering Scholarship, National Aeronautics and Space Administration
    1997 - 1999Academic Achievement Scholarship, Sachs Foundation
    1997Scholarship for Community Service and Leadership, Denver Youth Development Institute

    Collapse Overview 
    Collapse overview
    Extensive postdoctoral training and experience in metabolomics applications to toxicology, clinical research, and nutrition as gained at Oregon State University, National Jewish Health (Affiliate), and the University of Colorado, Denver have afforded me multidisciplinary credentials for clinical, translational, and basic science research. I have award-winning experience and leadership in exploiting the benefits of untargeted metabolomics in the discovery of novel indicators of dietary deficiency and potential early onset of disease states via impacted pathways. My pre and postdoctoral research has involved toxicological research in garlic organosulfide compounds for breast cancer prevention; the role of micronutrients, specifically zinc, in altering life-time health outcomes including developmental, reproductive health, and cardiovascular effects in the zebrafish model; and the developmental toxicity of arsenic exposure. In addition, as a member of the University of Colorado Mass Spectrometry Core, I have had the privilege to contribute to several projects evaluating lung disease health disparities in children and African Americans. My diverse academic training and experience provide unique credentials for providing expertise in the influence of pharmaceutical, environmental, and dietary influences in disease susceptibility, causation, and outcomes. The theme of my career will continue to be defined by my research question: how do nutrition and environmental exposures alter susceptibilities and disease outcomes in underrepresented populations, women, and children. Through this grant, I will be able to propel my career and become an expert in foodomics/nutritional metabolomics, through the utilization and development of untargeted and targeted LC/MS assays to detect dietary metabolites following consumption. The data acquired from this study will help to elucidate the mechanisms of food-derived compounds in altering biochemical pathways related to optimal health and disease outcomes, providing stronger and much needed evidence for disease prevention using nutritional intervention.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Beaver LM, Nkrumah-Elie YM, Truong L, Barton CL, Knecht AL, Gonnerman GD, Wong CP, Tanguay RL, Ho E. Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model. J Nutr Biochem. 2017 May; 43:78-87. PMID: 28268202.
      View in: PubMed
    2. Elie MR, Choi J, Nkrumah-Elie YM, Gonnerman GD, Stevens JF, Tanguay RL. Metabolomic analysis to define and compare the effects of PAHs and oxygenated PAHs in developing zebrafish. Environ Res. 2015 Jul; 140:502-10. PMID: 26001975; PMCID: PMC4492807.
    3. Nkrumah-Elie YM, Reuben JS, Hudson AM, Taka E, Badisa R, Ardley T, Israel B, Sadrud-Din SY, Oriaku ET, Darling-Reed SF. The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells. Nutr Cancer. 2012; 64(7):1112-21. PMID: 23006051; PMCID: PMC3559020.
    4. Nkrumah-Elie YM, Reuben JS, Hudson A, Taka E, Badisa R, Ardley T, Israel B, Sadrud-Din SY, Oriaku E, Darling-Reed SF. Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells. Food Chem Toxicol. 2012 Jul; 50(7):2524-30. PMID: 22525868; PMCID: PMC3374924.
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