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David Lynch

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-RAD General Operations
Phone303/315-7171

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Raghu G, Ghazipura M, Fleming TR, Aronson KI, Behr J, Brown KK, Flaherty KR, Kazerooni EA, Maher TM, Richeldi L, Lasky JA, Swigris JJ, Busch R, Garrard L, Ahn DH, Li J, Puthawala K, Rodal G, Seymour S, Weir N, Danoff SK, Ettinger N, Goldin J, Glassberg MK, Kawano-Dourado L, Khalil N, Lancaster L, Lynch DA, Mageto Y, Noth I, Shore JE, Wijsenbeek M, Brown R, Grogan D, Ivey D, Golinska P, Karimi-Shah B, Martinez FJ. Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency. Am J Respir Crit Care Med. 2024 Mar 15; 209(6):647-669. PMID: 38174955.
      View in: PubMed
    2. Oh AS, Lynch DA, Swigris JJ, Baraghoshi D, Dyer DS, Hale VA, Koelsch TL, Marrocchio C, Parker KN, Teague SD, Flaherty KR, Humphries SM. Deep Learning-based Fibrosis Extent on Computed Tomography Predicts Outcome of Fibrosing Interstitial Lung Disease Independent of Visually Assessed Computed Tomography Pattern. Ann Am Thorac Soc. 2024 Feb; 21(2):218-227. PMID: 37696027.
      View in: PubMed
    3. DeBoer EM, Weinman JP, Ley-Zaporozhan J, Griese M, Deterding R, Lynch DA, Humphries SM, Jacob J. Imaging of pulmonary fibrosis in children: A review, with proposed diagnostic criteria. Pediatr Pulmonol. 2024 Apr; 59(4):845-854. PMID: 38214442.
      View in: PubMed
    4. Humphries SM, Thieke D, Baraghoshi D, Strand MJ, Swigris JJ, Chae KJ, Hwang HJ, Oh AS, Flaherty KR, Adegunsoye A, Jablonski R, Lee CT, Husain AN, Chung JH, Strek ME, Lynch DA. Deep Learning Classification of Usual Interstitial Pneumonia Predicts Outcomes. Am J Respir Crit Care Med. 2024 Jan 11. PMID: 38207093.
      View in: PubMed
    5. Vegas S?nchez-Ferrero G, D?az AA, Ash SY, Baraghoshi D, Strand M, Crapo JD, Silverman EK, Humphries SM, Washko GR, Lynch DA, San Jos? Est?par R. Quantification of Emphysema Progression at CT Using Simultaneous Volume, Noise, and Bias Lung Density Correction. Radiology. 2024 Jan; 310(1):e231632. PMID: 38165244.
      View in: PubMed
    6. Cha MJ, Solomon JJ, Lee JE, Choi H, Chae KJ, Lee KS, Lynch DA. Chronic Lung Injury after COVID-19 Pneumonia: Clinical, Radiologic, and Histopathologic Perspectives. Radiology. 2024 Jan; 310(1):e231643. PMID: 38193836.
      View in: PubMed
    7. Miller JE, Taylor-Cousar JL, Humphries SM, Khatiwada A, Chen H, Wilson A, Vladar EK, Lynch DA, Li DA, Beswick DM. Chronic rhinosinusitis and olfaction after highly effective modulator therapy: The role of individual sinus inflammation. Int Forum Allergy Rhinol. 2023 Dec 26. PMID: 38146638.
      View in: PubMed
    8. Desai SR, Sivarasan N, Johannson KA, George PM, Culver DA, Devaraj A, Lynch DA, Milne D, Renzoni E, Nunes H, Sverzellati N, Spagnolo P, Baughman RP, Yadav R, Piciucchi S, Walsh SLF, Kouranos V, Wells AU. High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study. Lancet Respir Med. 2023 Dec 14. PMID: 38104579.
      View in: PubMed
    9. Lynch DR, Rojsajjakul T, Subramony SH, Perlman SL, Keita M, Mesaros C, Blair IA. Frataxin analysis using triple quadrupole mass spectrometry: application to a large heterogeneous clinical cohort. J Neurol. 2024 Apr; 271(4):1844-1849. PMID: 38063871.
      View in: PubMed
    10. Marrocchio C, Humphries SM, Lynch DA. Chest Computed Tomography Findings in Unilateral Pulmonary Fibrosis Secondary to Chronic Hypoperfusion. J Thorac Imaging. 2023 Nov 24. PMID: 38095281.
      View in: PubMed
    11. Bell AJ, Pal R, Labaki WW, Hoff BA, Wang JM, Murray S, Kazerooni EA, Galban S, Lynch DA, Humphries SM, Martinez FJ, Hatt CR, Han MK, Ram S, Galban CJ. Quantitative CT of Normal Lung Parenchyma and Small Airways Disease Topologies are Associated With COPD Severity and Progression. medRxiv. 2023 Nov 20. PMID: 37333382.
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    12. Crapo JD, Gupta A, Lynch DA, Turner AM, Mroz RM, Janssens W, Ludwig-Sengpiel A, Koegler H, Eleftheraki A, Risse F, Diefenbach C. Baseline characteristics from a 3-year longitudinal study to phenotype subjects with COPD: the FOOTPRINTS study. Respir Res. 2023 Nov 17; 24(1):290. PMID: 37978492.
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    13. Baraghoshi D, Strand M, Humphries SM, San Jos? Est?par R, Vegas Sanchez-Ferrero G, Charbonnier JP, Latisenko R, Silverman EK, Crapo JD, Lynch DA. Erratum for: Quantitative CT Evaluation of Emphysema Progression over 10 Years in the COPDGene Study. Radiology. 2023 Nov; 309(2):e239028. PMID: 38015087.
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    14. Escalon JG, Podolanczuk AJ, Aronson KI, Legasto AC, Gruden JF, Lynch DA, Rachid L, Rabkova Y, Steinberger S. Practice patterns in reporting interstitial lung abnormality at a tertiary academic medical center. Clin Imaging. 2023 Dec; 104:109996. PMID: 37862912.
      View in: PubMed
    15. Castaldi PJ, Xu Z, Young KA, Hokanson JE, Lynch DA, Humphries SM, Ross JC, Cho MH, Hersh CP, Crapo JD, Strand M, Silverman EK. Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease. Am J Epidemiol. 2023 10 10; 192(10):1647-1658. PMID: 37160347.
      View in: PubMed
    16. Beswick DM, Khatiwada A, Miller JE, Humphries SM, Wilson A, Vladar EK, Lynch DA, Taylor-Cousar JL. Impact of highly effective modulator therapy on chronic rhinosinusitis and health status: 2-year follow-up. J Cyst Fibros. 2023 Oct 05. PMID: 37805356.
      View in: PubMed
    17. Zeng S, Luo G, Lynch DA, Bowler RP, Arjomandi M. Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort. ERJ Open Res. 2023 Sep; 9(5). PMID: 37727675.
      View in: PubMed
    18. Ash SY, Choi B, Oh A, Lynch DA, Humphries SM. Deep Learning Assessment of Progression of Emphysema and Fibrotic Interstitial Lung Abnormality. Am J Respir Crit Care Med. 2023 09 15; 208(6):666-675. PMID: 37364281.
      View in: PubMed
    19. Rose CS, Zell-Baran LM, Cool C, Moore CM, Wolff J, Oh AS, Koelsch T, Richards JC, Krefft SD, Wilson CG, Lynch DA. Findings on High Resolution Computed Tomography in Symptomatic Veterans with Deployment-Related Lung Disease. J Thorac Imaging. 2023 Sep 15. PMID: 37732711.
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    20. Motahari A, Barr RG, Han MK, Anderson WH, Barjaktarevic I, Bleecker ER, Comellas AP, Cooper CB, Couper DJ, Hansel NN, Kanner RE, Kazerooni EA, Lynch DA, Martinez FJ, Newell JD, Schroeder JD, Smith BM, Woodruff PG, Hoffman EA. Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2023 09 15; 208(6):657-665. PMID: 37490608.
      View in: PubMed
    21. Raoof S, Braman S, Make B, Lynch D. Response. Chest. 2023 09; 164(3):e86. PMID: 37689480.
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    22. Seabury J, Rosero S, Varma A, Weinstein J, Engebrecht C, Dilek N, Heatwole J, Alexandrou D, Cohen B, Larkindale J, Lynch DR, Park C, Subramony SH, Wagner E, Walther S, Wells M, Zizzi C, Heatwole C. Friedreich's Ataxia-Health Index: Development and Validation of a Novel Disease-Specific Patient-Reported Outcome Measure. Neurol Clin Pract. 2023 Oct; 13(5):e200180. PMID: 37646046.
      View in: PubMed
    23. Vizcarra JA, Paul RA, Hamedani AG, Lynch DR, Aamodt WW. Clinical Reasoning: A 48-Year-Old Man With Spasticity and Progressive Ataxia. Neurology. 2023 10 24; 101(17):e1747-e1752. PMID: 37596043.
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    24. Arjomandi M, Zeng S, Chen J, Bhatt SP, Abtin F, Barjaktarevic I, Barr RG, Bleecker ER, Buhr RG, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Fortis S, Han MK, Hansel NN, Hoffman EA, Hokanson JE, Kaner RJ, Kanner RE, Krishnan JA, Labaki WW, Lynch DA, Ortega VE, Peters SP, Woodruff PG, Cooper CB, Bowler RP, Paine R, Rennard SI, Tashkin DP. Changes in Lung Volumes with Spirometric Disease Progression in COPD. Chronic Obstr Pulm Dis. 2023 Jul 26; 10(3):270-285. PMID: 37199719.
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    25. Oh AS, Lynch DA. Diagnostic Guidelines for Usual Interstitial Pneumonia and Progressive Pulmonary Fibrosis. J Thorac Imaging. 2023 09 01; 38(5):W75-W76. PMID: 37423616.
      View in: PubMed
    26. Comellas AP, Newell JD, Kirby M, Sieren JP, Peterson S, Hatt C, Galban CJ, Kazerooni EA, Lynch DA, Han MK, Hoffman EA. Residual Volume versus FRC Computed Tomography Assessment of Functional Small Airway Disease in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2023 06 01; 207(11):1536-1539. PMID: 36977314.
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    27. Hata A, Hino T, Li Y, Johkoh T, Christiani DC, Lynch DA, Cho MH, Silverman EK, Hunninghake GM, Hatabu H. Traction Bronchiectasis/Bronchiolectasis in Interstitial Lung Abnormality: Follow-up in the COPDGene Study. Am J Respir Crit Care Med. 2023 05 15; 207(10):1395-1398. PMID: 36898128.
      View in: PubMed
    28. Koslow M, Lynch DA, Cool CD, Groshong SD, Downey GP. Lymphangioleiomyomatosis and Other Cystic Lung Diseases. Immunol Allergy Clin North Am. 2023 05; 43(2):359-377. PMID: 37055093.
      View in: PubMed
    29. Chae KJ, Lim S, Seo JB, Hwang HJ, Choi H, Lynch D, Jin GY. Interstitial Lung Abnormalities at CT in the Korean National Lung Cancer Screening Program: Prevalence and Deep Learning-based Texture Analysis. Radiology. 2023 05; 307(4):e222828. PMID: 37097142.
      View in: PubMed
    30. Baraghoshi D, Strand M, Humphries SM, San Jos? Est?par R, Vegas Sanchez-Ferrero G, Charbonnier JP, Latisenko R, Silverman EK, Crapo JD, Lynch DA. Quantitative CT Evaluation of Emphysema Progression over 10 Years in the COPDGene Study. Radiology. 2023 05; 307(4):e222786. PMID: 37039685.
      View in: PubMed
    31. Fern?ndez P?rez ER, Crooks JL, Lynch DA, Humphries SM, Koelsch TL, Swigris JJ, Solomon JJ, Mohning MP, Groshong SD, Fier K. Pirfenidone in fibrotic hypersensitivity pneumonitis: a double-blind, randomised clinical trial of efficacy and safety. Thorax. 2023 11; 78(11):1097-1104. PMID: 37028940.
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    32. Mulshine JL, Aldig? CR, Ambrose LF, Armato SG, Avila RS, Cham M, Estepar RSJ, Fain SB, Gazourian L, Gierada DS, Hatt C, Henschke CI, Hoyos J, Lynch DA, McGlothlin AK, Oudkerk M, Pasquinelli M, Pinsky P, Pyenson B, Rizzo AA, Ross SM, Schmitz KH, Silva M, Okwuosa T, Washko G, Wisnivesky J, Yankelevitz DF, Zulueta JJ. Emphysema Detection in the Course of Lung Cancer Screening: Optimizing a Rare Opportunity to Impact Population Health. Ann Am Thorac Soc. 2023 04; 20(4):499-503. PMID: 36490389.
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    33. Rodden LN, Rummey C, Kessler S, Wilson RB, Lynch DR. A Novel Metric for Predicting Severity of Disease Features in Friedreich's Ataxia. Mov Disord. 2023 06; 38(6):970-977. PMID: 36928898.
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    34. Raoof S, Shah M, Make B, Allaqaband H, Bowler R, Fernando S, Greenberg H, Han MK, Hogg J, Humphries S, Lee KS, Lynch D, Machnicki S, Mehta A, Mina B, Naidich D, Naidich J, Naqvi Z, Ohno Y, Regan E, Travis WD, Washko G, Braman S. Lung Imaging in COPD Part 1: Clinical Usefulness. Chest. 2023 07; 164(1):69-84. PMID: 36907372.
      View in: PubMed
    35. Raoof S, Shah M, Braman S, Agrawal A, Allaqaband H, Bowler R, Castaldi P, DeMeo D, Fernando S, Hall CS, Han MK, Hogg J, Humphries S, Lee HY, Lee KS, Lynch D, Machnicki S, Mehta A, Mehta S, Mina B, Naidich D, Naidich J, Ohno Y, Regan E, van Beek EJR, Washko G, Make B. Lung Imaging in COPD Part 2: Emerging Concepts. Chest. 2023 08; 164(2):339-354. PMID: 36907375.
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    36. Steele MP, Peljto AL, Mathai SK, Humphries S, Bang TJ, Oh A, Teague S, Cicchetti G, Sigakis C, Kropski JA, Loyd JE, Blackwell TS, Brown KK, Schwarz MI, Warren RA, Powers J, Walts AD, Markin C, Fingerlin TE, Yang IV, Lynch DA, Lee JS, Schwartz DA. Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort. Am J Respir Crit Care Med. 2023 03 01; 207(5):587-593. PMID: 36094461.
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    37. Profeta V, McIntyre K, Wells M, Park C, Lynch DR. Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia. Expert Opin Investig Drugs. 2023 Jan; 32(1):5-16. PMID: 36708320.
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    38. Hsia CCW, Bates JHT, Driehuys B, Fain SB, Goldin JG, Hoffman EA, Hogg JC, Levin DL, Lynch DA, Ochs M, Parraga G, Prisk GK, Smith BM, Tawhai M, Vidal Melo MF, Woods JC, Hopkins SR. Quantitative Imaging Metrics for the Assessment of Pulmonary Pathophysiology: An Official American Thoracic Society and Fleischner Society Joint Workshop Report. Ann Am Thorac Soc. 2023 02; 20(2):161-195. PMID: 36723475.
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    39. Rose JA, Menon AA, Hino T, Hata A, Nishino M, Lynch DA, Rosas IO, El-Chemaly S, Raby BA, Ash SY, Choi B, Washko GR, Silverman EK, Cho MH, Hatabu H, Putman RK, Hunninghake GM. Suspected Interstitial Lung Disease in COPDGene Study. Am J Respir Crit Care Med. 2023 01 01; 207(1):60-68. PMID: 35930450.
      View in: PubMed
    40. Lynch DR, Mathews KD, Perlman S, Zesiewicz T, Subramony S, Omidvar O, Vogel AP, Krtolica A, Litterman N, van der Ploeg L, Heerinckx F, Milner P, Midei M. Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia. J Neurol. 2023 Mar; 270(3):1615-1623. PMID: 36462055.
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    41. Abadi E, Jadick G, Lynch DA, Segars WP, Samei E. Emphysema Quantifications With CT Scan: Assessing the Effects of Acquisition Protocols and Imaging Parameters Using Virtual Imaging Trials. Chest. 2023 05; 163(5):1084-1100. PMID: 36462532.
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    42. Bhatt SP, Bodduluri S, Dransfield MT, Reinhardt JM, Crapo JD, Silverman EK, Humphries S, Lynch DA, Strand MJ. Acute Exacerbations Are Associated with Progression of Emphysema. Ann Am Thorac Soc. 2022 12; 19(12):2108-2111. PMID: 35914221.
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    43. Yuan NF, Hasenstab K, Retson T, Conrad DJ, Lynch DA, Hsiao A. Unsupervised Learning Identifies Computed Tomographic Measurements as Primary Drivers of Progression, Exacerbation, and Mortality in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 Dec; 19(12):1993-2002. PMID: 35830591.
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    44. Remy-Jardin M, Leung ANC, Lynch DA. Chest Imaging. Semin Respir Crit Care Med. 2022 Dec; 43(6):763. PMID: 36442472.
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    45. Seabury J, Alexandrou D, Dilek N, Cohen B, Heatwole J, Larkindale J, Lynch DR, Park C, Rosero S, Subramony SH, Varma A, Wagner E, Walther S, Weinstein J, Wells M, Zizzi C, Heatwole C. Patient-Reported Impact of Symptoms in Friedreich Ataxia. Neurology. 2023 02 21; 100(8):e808-e821. PMID: 36443012.
      View in: PubMed
    46. Marrocchio C, Lynch DA. High-Resolution Computed Tomography of Nonfibrotic Interstitial Lung Disease. Semin Respir Crit Care Med. 2022 Dec; 43(6):780-791. PMID: 36442473.
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    47. Walsh SLF, Mackintosh JA, Calandriello L, Silva M, Sverzellati N, Larici AR, Humphries SM, Lynch DA, Jo HE, Glaspole I, Grainge C, Goh N, Hopkins PMA, Moodley Y, Reynolds PN, Zappala C, Keir G, Cooper WA, Mahar AM, Ellis S, Wells AU, Corte TJ. Deep Learning-based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography. Am J Respir Crit Care Med. 2022 10 01; 206(7):883-891. PMID: 35696341.
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    48. Solomon JJ, Danoff SK, Woodhead FA, Hurwitz S, Maurer R, Glaspole I, Dellaripa PF, Gooptu B, Vassallo R, Cox PG, Flaherty KR, Adamali HI, Gibbons MA, Troy L, Forrest IA, Lasky JA, Spencer LG, Golden J, Scholand MB, Chaudhuri N, Perrella MA, Lynch DA, Chambers DC, Kolb M, Spino C, Raghu G, Goldberg HJ, Rosas IO. Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study. Lancet Respir Med. 2023 01; 11(1):87-96. PMID: 36075242.
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    49. Rodden LN, Rummey C, Dong YN, Lagedrost S, Regner S, Brocht A, Bushara K, Delatycki MB, Gomez CM, Mathews K, Murray S, Perlman S, Ravina B, Subramony SH, Wilmot G, Zesiewicz T, Bolotta A, Domissy A, Jespersen C, Ji B, Soragni E, Gottesfeld JM, Lynch DR. A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia. Front Mol Biosci. 2022; 9:933788. PMID: 36133907.
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    50. Oh AS, Lynch DA. Interstitial Lung Abnormality-Why Should I Care and What Should I Do About It? Radiol Clin North Am. 2022 Nov; 60(6):889-899. PMID: 36202476.
      View in: PubMed
    51. Lynch DA, Brown M, Saperstein A, Stefancic A, Medalia A. Assessing metamotivation in schizophrenia: A pilot study of the Brief Regulation of Motivation Scale (BRoMS). Psychiatry Res. 2022 11; 317:114799. PMID: 36037743.
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    52. Cottin V, Tomassetti S, Valenzuela C, Walsh SLF, Antoniou KM, Bonella F, Brown KK, Collard HR, Corte TJ, Flaherty KR, Johannson KA, Kolb M, Kreuter M, Inoue Y, Jenkins RG, Lee JS, Lynch DA, Maher TM, Martinez FJ, Molina-Molina M, Myers JL, Nathan SD, Poletti V, Quadrelli S, Raghu G, Rajan SK, Ravaglia C, Remy-Jardin M, Renzoni E, Richeldi LK, Spagnolo P, Troy L, Wijsenbeek M, Wilson KC, Wuyts W, Wells AU, Ryerson CJ. Integrating Clinical Probability into the Diagnostic Approach to Idiopathic Pulmonary Fibrosis: An International Working Group Perspective. Am J Respir Crit Care Med. 2022 08 01; 206(3):247-259. PMID: 35353660.
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    53. Strand M, Khatiwada A, Baraghoshi D, Lynch D, Silverman EK, Bhatt SP, Austin E, Regan EA, Boriek AM, Crapo JD. Predicting COPD Progression in Current and Former Smokers Using a Joint Model for Forced Expiratory Volume in 1 Second and Forced Expiratory Volume in 1 Second to Forced Vital Capacity Ratio. Chronic Obstr Pulm Dis. 2022 Jul 29; 9(3):439-453. PMID: 35905755.
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    54. Humphries SM, Mackintosh JA, Jo HE, Walsh SLF, Silva M, Calandriello L, Chapman S, Ellis S, Glaspole I, Goh N, Grainge C, Hopkins PMA, Keir GJ, Moodley Y, Reynolds PN, Walters EH, Baraghoshi D, Wells AU, Lynch DA, Corte TJ. Quantitative computed tomography predicts outcomes in idiopathic pulmonary fibrosis. Respirology. 2022 Dec; 27(12):1045-1053. PMID: 35875881.
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    55. Howe AS, Lynch DA. Cytokine alterations in pediatric internalizing disorders: Systematic review and exploratory multi-variate meta-analysis. Brain Behav Immun Health. 2022 Oct; 24:100490. PMID: 35880170.
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    56. Wang D, Ho ES, Cotticelli MG, Xu P, Napierala JS, Hauser LA, Napierala M, Himes BE, Wilson RB, Lynch DR, Mesaros C. Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia. J Lipid Res. 2022 09; 63(9):100255. PMID: 35850241.
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    57. Choi B, Adan N, Doyle TJ, San Jos? Est?par R, Harmouche R, Humphries SM, Moll M, Cho MH, Putman RK, Hunninghake GM, Kalhan R, Liu GY, Diaz AA, Mason SE, Rahaghi FN, Pistenmaa CL, Enzer N, Poynton C, S?nchez-Ferrero GV, Ross JC, Lynch DA, Martinez FJ, Han MK, Bowler RP, Wilson DO, Rosas IO, Washko GR, San Jos? Est?par R, Ash SY. Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts. Chest. 2023 01; 163(1):164-175. PMID: 35780812.
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    58. Keita M, McIntyre K, Rodden LN, Schadt K, Lynch DR. Friedreich ataxia: clinical features and new developments. Neurodegener Dis Manag. 2022 10; 12(5):267-283. PMID: 35766110.
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    59. Marinescu DC, Raghu G, Remy-Jardin M, Travis WD, Adegunsoye A, Beasley MB, Chung JH, Churg A, Cottin V, Egashira R, Fern?ndez P?rez ER, Inoue Y, Johannson KA, Kazerooni EA, Khor YH, Lynch DA, M?ller NL, Myers JL, Nicholson AG, Rajan S, Saito-Koyama R, Troy L, Walsh SLF, Wells AU, Wijsenbeek MS, Wright JL, Ryerson CJ. Integration and Application of Clinical Practice Guidelines for the Diagnosis of Idiopathic Pulmonary Fibrosis and Fibrotic Hypersensitivity Pneumonitis. Chest. 2022 Sep; 162(3):614-629. PMID: 35738345.
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    60. Hata A, Hino T, Putman RK, Yanagawa M, Hida T, Menon AA, Honda O, Yamada Y, Nishino M, Araki T, Valtchinov VI, Jinzaki M, Honda H, Ishigami K, Johkoh T, Tomiyama N, Christiani DC, Lynch DA, San Jos? Est?par R, Washko GR, Cho MH, Silverman EK, Hunninghake GM, Hatabu H. Traction Bronchiectasis/Bronchiolectasis on CT Scans in Relationship to Clinical Outcomes and Mortality: The COPDGene Study. Radiology. 2022 09; 304(3):694-701. PMID: 35638925.
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    61. Beswick DM, Humphries SM, Miller JE, Balkissoon CD, Khatiwada A, Vladar EK, Ramakrishnan VR, Lynch DA, Taylor-Cousar JL. Objective and patient-based measures of chronic rhinosinusitis in people with cystic fibrosis treated with highly effective modulator therapy. Int Forum Allergy Rhinol. 2022 11; 12(11):1435-1438. PMID: 35595546.
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    62. Oh AS, Baraghoshi D, Lynch DA, Ash SY, Crapo JD, Humphries SM. Emphysema Progression at CT by Deep Learning Predicts Functional Impairment and Mortality: Results from the COPDGene Study. Radiology. 2022 09; 304(3):672-679. PMID: 35579519.
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    63. Rodden LN, Rummey C, Dong YN, Lynch DR. Clinical Evidence for Variegated Silencing in Patients With Friedreich Ataxia. Neurol Genet. 2022 Jun; 8(3):e683. PMID: 35620135.
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    64. Nick JA, Dedrick RM, Gray AL, Vladar EK, Smith BE, Freeman KG, Malcolm KC, Epperson LE, Hasan NA, Hendrix J, Callahan K, Walton K, Vestal B, Wheeler E, Rysavy NM, Poch K, Caceres S, Lovell VK, Hisert KB, de Moura VC, Chatterjee D, De P, Weakly N, Martiniano SL, Lynch DA, Daley CL, Strong M, Jia F, Hatfull GF, Davidson RM. Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection. Cell. 2022 05 26; 185(11):1860-1874.e12. PMID: 35568033.
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    65. Raghu G, Remy-Jardin M, Richeldi L, Thomson CC, Inoue Y, Johkoh T, Kreuter M, Lynch DA, Maher TM, Martinez FJ, Molina-Molina M, Myers JL, Nicholson AG, Ryerson CJ, Strek ME, Troy LK, Wijsenbeek M, Mammen MJ, Hossain T, Bissell BD, Herman DD, Hon SM, Kheir F, Khor YH, Macrea M, Antoniou KM, Bouros D, Buendia-Roldan I, Caro F, Crestani B, Ho L, Morisset J, Olson AL, Podolanczuk A, Poletti V, Selman M, Ewing T, Jones S, Knight SL, Ghazipura M, Wilson KC. Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2022 05 01; 205(9):e18-e47. PMID: 35486072.
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    66. Wang Q, Laboureur L, Weng L, Eskenazi NM, Hauser LA, Mesaros C, Lynch DR, Blair IA. Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood. Front Neurosci. 2022; 16:874768. PMID: 35573317.
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    67. Zell-Baran LM, Humphries SM, Moore CM, Lynch DA, Charbonnier JP, Oh AS, Rose CS. Quantitative imaging analysis detects subtle airway abnormalities in symptomatic military deployers. BMC Pulm Med. 2022 Apr 27; 22(1):163. PMID: 35477425.
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    68. Yang SR, Beasley MB, Churg A, Colby TV, Fern?ndez P?rez ER, Lynch D, M?ller NL, Travis WD. Diagnosis of Hypersensitivity Pneumonitis: Review and Summary of American College of Chest Physicians Statement. Am J Surg Pathol. 2022 04 01; 46(4):e71-e93. PMID: 34753865.
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    69. Lynch DA, Chung JH, Kanne JP, Meyer CA. Radiologic Classification of Black Lung: Time for a New Gold Standard? Ann Am Thorac Soc. 2022 04; 19(4):701-702. PMID: 35030054.
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    445. Mazzulli JR, Mishizen AJ, Giasson BI, Lynch DR, Thomas SA, Nakashima A, Nagatsu T, Ota A, Ischiropoulos H. Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. J Neurosci. 2006 Sep 27; 26(39):10068-78. PMID: 17005870.
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    446. Tanaka N, Kim JS, Bates CA, Brown KK, Cool CD, Newell JD, Lynch DA. Lung diseases in patients with common variable immunodeficiency: chest radiographic, and computed tomographic findings. J Comput Assist Tomogr. 2006 Sep-Oct; 30(5):828-38. PMID: 16954938.
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    447. Swigris JJ, Olson AL, Fischer A, Lynch DA, Cosgrove GP, Frankel SK, Meehan RT, Brown KK. Mycophenolate mofetil is safe, well tolerated, and preserves lung function in patients with connective tissue disease-related interstitial lung disease. Chest. 2006 Jul; 130(1):30-6. PMID: 16840379.
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    448. Misumi S, Lynch DA. Idiopathic pulmonary fibrosis/usual interstitial pneumonia: imaging diagnosis, spectrum of abnormalities, and temporal progression. Proc Am Thorac Soc. 2006 Jun; 3(4):307-14. PMID: 16738194.
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    449. Wu HY, Lynch DR. Calpain and synaptic function. Mol Neurobiol. 2006 Jun; 33(3):215-36. PMID: 16954597.
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    450. Quaife RA, Chen MY, Lynch D, Badesch DB, Groves BM, Wolfel E, Robertson AD, Bristow MR, Voelkel NF. Importance of right ventricular end-systolic regional wall stress in idiopathic pulmonary arterial hypertension: a new method for estimation of right ventricular wall stress. Eur J Med Res. 2006 May 05; 11(5):214-20. PMID: 16723296.
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    451. Kim JS, Tanaka N, Newell JD, Degroote MA, Fulton K, Huitt G, Lynch DA. Nontuberculous mycobacterial infection: CT scan findings, genotype, and treatment responsiveness. Chest. 2005 Dec; 128(6):3863-9. PMID: 16354855.
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    452. Pipavath SJ, Lynch DA, Cool C, Brown KK, Newell JD. Radiologic and pathologic features of bronchiolitis. AJR Am J Roentgenol. 2005 Aug; 185(2):354-63. PMID: 16037505.
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    453. Lynch DA, Travis WD, M?ller NL, Galvin JR, Hansell DM, Grenier PA, King TE. Idiopathic interstitial pneumonias: CT features. Radiology. 2005 Jul; 236(1):10-21. PMID: 15987960.
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    454. Waxman EA, Lynch DR. N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. J Biol Chem. 2005 Aug 12; 280(32):29322-33. PMID: 15967799.
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    455. Lynch DA, Godwin JD, Safrin S, Starko KM, Hormel P, Brown KK, Raghu G, King TE, Bradford WZ, Schwartz DA, Richard Webb W. High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):488-93. PMID: 15894598.
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    456. Elliot TL, Lynch DA, Newell JD, Cool C, Tuder R, Markopoulou K, Veve R, Brown KK. High-resolution computed tomography features of nonspecific interstitial pneumonia and usual interstitial pneumonia. J Comput Assist Tomogr. 2005 May-Jun; 29(3):339-45. PMID: 15891504.
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    457. Fink JN, Ortega HG, Reynolds HY, Cormier YF, Fan LL, Franks TJ, Kreiss K, Kunkel S, Lynch D, Quirce S, Rose C, Schleimer RP, Schuyler MR, Selman M, Trout D, Yoshizawa Y. Needs and opportunities for research in hypersensitivity pneumonitis. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):792-8. PMID: 15657460.
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    458. Frankel SK, Cool CD, Lynch DA, Brown KK. Idiopathic pleuroparenchymal fibroelastosis: description of a novel clinicopathologic entity. Chest. 2004 Dec; 126(6):2007-13. PMID: 15596706.
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    459. Baybis M, Lynch D, Lee A, Patel A, McKhann G, Chugani D, J Kupsky W, Aronica E, Crino PB. Altered expression of neurotransmitter-receptor subunit and uptake site mRNAs in hemimegalencephaly. Epilepsia. 2004 Dec; 45(12):1517-24. PMID: 15571509.
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    460. Hodara R, Norris EH, Giasson BI, Mishizen-Eberz AJ, Lynch DR, Lee VM, Ischiropoulos H. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. J Biol Chem. 2004 Nov 12; 279(46):47746-53. PMID: 15364911.
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    461. Bearden CE, Jawad AF, Lynch DR, Sokol S, Kanes SJ, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ. Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome. Am J Psychiatry. 2004 Sep; 161(9):1700-2. PMID: 15337663.
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    462. Bates CA, Ellison MC, Lynch DA, Cool CD, Brown KK, Routes JM. Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency. J Allergy Clin Immunol. 2004 Aug; 114(2):415-21. PMID: 15316526.
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    463. Tanaka N, Kim JS, Newell JD, Brown KK, Cool CD, Meehan R, Emoto T, Matsumoto T, Lynch DA. Rheumatoid arthritis-related lung diseases: CT findings. Radiology. 2004 Jul; 232(1):81-91. PMID: 15166329.
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    464. Tanaka N, Newell JD, Brown KK, Cool CD, Lynch DA. Collagen vascular disease-related lung disease: high-resolution computed tomography findings based on the pathologic classification. J Comput Assist Tomogr. 2004 May-Jun; 28(3):351-60. PMID: 15100540.
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    465. Hunninghake GW, Lynch DA, Galvin JR, Gross BH, M?ller N, Schwartz DA, King TE, Lynch JP, Hegele R, Waldron J, Colby TV, Hogg JC. Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. Chest. 2003 Oct; 124(4):1215-23. PMID: 14555549.
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    466. Lynch DA. Fibrotic idiopathic interstitial pneumonia: high-resolution computed tomography considerations. Semin Respir Crit Care Med. 2003 Aug; 24(4):365-76. PMID: 16088558.
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    467. Lynch DR, Mozley PD, Sokol S, Maas NM, Balcer LJ, Siderowf AD. Lack of effect of polymorphisms in dopamine metabolism related genes on imaging of TRODAT-1 in striatum of asymptomatic volunteers and patients with Parkinson's disease. Mov Disord. 2003 Jul; 18(7):804-12. PMID: 12815660.
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    468. Best AC, Lynch AM, Bozic CM, Miller D, Grunwald GK, Lynch DA. Quantitative CT indexes in idiopathic pulmonary fibrosis: relationship with physiologic impairment. Radiology. 2003 Aug; 228(2):407-14. PMID: 12802000.
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    469. Tanaka N, Matsumoto T, Miura G, Emoto T, Matsunaga N, Ueda K, Lynch DA. Air trapping at CT: high prevalence in asymptomatic subjects with normal pulmonary function. Radiology. 2003 Jun; 227(3):776-85. PMID: 12702825.
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    470. Weiland DA, Lynch DA, Jensen SP, Newell JD, Miller DE, Crausman RS, Kuhn C, Kern DG. Thin-section CT findings in flock worker's lung, a work-related interstitial lung disease. Radiology. 2003 Apr; 227(1):222-31. PMID: 12668748.
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    471. Lee JS, Lynch DA, Sharma S, Brown KK, M?ller NL. Organizing pneumonia: prognostic implication of high-resolution computed tomography features. J Comput Assist Tomogr. 2003 Mar-Apr; 27(2):260-5. PMID: 12703023.
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    472. Garg K, Lynch DA. Imaging of thoracic occupational and environmental malignancies. J Thorac Imaging. 2002 Jul; 17(3):198-210. PMID: 12082371.
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    473. Lee JS, Brown KK, Cool C, Lynch DA. Diffuse pulmonary neuroendocrine cell hyperplasia: radiologic and clinical features. J Comput Assist Tomogr. 2002 Mar-Apr; 26(2):180-4. PMID: 11884770.
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    474. Lee KH, Lee JS, Lynch DA, Song KS, Lim TH. The radiologic differential diagnosis of diffuse lung diseases characterized by multiple cysts or cavities. J Comput Assist Tomogr. 2002 Jan-Feb; 26(1):5-12. PMID: 11801898.
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    475. Park JS, Brown KK, Tuder RM, Hale VA, King TE, Lynch DA. Respiratory bronchiolitis-associated interstitial lung disease: radiologic features with clinical and pathologic correlation. J Comput Assist Tomogr. 2002 Jan-Feb; 26(1):13-20. PMID: 11801899.
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